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    Effects of an exercise therapy targeting knee kinetics on pain, function, and gait kinetics in patients with knee osteoarthritis: A randomized clinical trial

    , Article Adapted Physical Activity Quarterly ; Volume 38, Issue 3 , 2021 , Pages 377-395 ; 07365829 (ISSN) Bokaeian, H. R ; Esfandiarpour, F ; Zahednejad, S ; Kouhzad Mohammadi, H ; Farahmand, F ; Sharif University of Technology
    Human Kinetics Publishers Inc  2021
    Abstract
    In this study, the effects of an exercise therapy comprising yoga exercises and medial-thrust gait (YogaMT) on lower-extremity kinetics, pain, and function in patients with medial knee osteoarthritis were investigated. Fifty-nine patients were randomly allocated to three treatment groups: (a) the YogaMT group practiced yoga exercises and medial thrust gait, (b) the knee-strengthening group performed quadriceps-and hamstring-strengthening exercises, and (c) the treadmill walking group practiced normal treadmill walking in 12 supervised sessions. The adduction and flexion moments of the hip, knee, and ankle; pain intensity; and 2-min walking test were assessed before and after treatment and at... 

    The effect of lumbosacral orthosis on the thickness of deep trunk muscles using ultrasound imaging: a randomized controlled trial in patients with chronic low back pain

    , Article American Journal of Physical Medicine and Rehabilitation ; Volume 98, Issue 7 , 2019 , Pages 536-544 ; 08949115 (ISSN) Azadinia, F ; Takamjani, I. E ; Kamyab, M ; Kalbassi, G ; Sarrafzadeh, J ; Parnianpour, M ; Sharif University of Technology
    Lippincott Williams and Wilkins  2019
    Abstract
    Objective This study was conducted to evaluate the changes occurring in the thickness of deep trunk muscles, measured using ultrasound imaging, after 4 wks of lumbosacral orthosis use in conjunction with routine physical therapy. Design This parallel-group, randomized, controlled trial was conducted on 44 patients with nonspecific chronic low back pain, randomly allocated to the experimental and control groups. Both groups received eight sessions of physical therapy twice per week for 4 wks. The experimental group wore nonextensible lumbosacral orthosis, in addition to undergoing routine physical therapy. The thickness of the transversus abdominis, obliquus internus, and lumbar multifidus... 

    The effect of a training program on body composition, growth hormone, insulin and insulin-like growth factor 1 in overweight female college students

    , Article Gazzetta Medica Italiana Archivio per le Scienze Mediche ; Volume 171, Issue 4 , 2012 , Pages 409-416 ; 03933660 (ISSN) Gholipour, M ; Tabrizi, A ; Sharif University of Technology
    Abstract
    Aim. The aim of this study was to determine the effect of a training program on body composition, GH, IGF-1 and insulin in overweight and obese female college students. Methods. The 17 overweight college student females divided into 2 groups: Experimental group (E) with 3 sessions per week, 6 weeks duration (N=9,Age=18.9 ± 1.3,BMI= 28.8 ± 2.6), and non-exercising control group (C) (N=8, Age=19.3 ± 1.8, BMI=26.3 ± 0.9). All measures included Vo2max, body composition, IGF-1, GH and insulin were done at baseline and following the protocol. Results. The calorie intake increased in both groups when compared to the baseline. The Vo2max increased statistically significant in E, and decreased in C.... 

    The acute effects of intermittent treadmill running on hunger and plasma acylated ghrelin concentration in individuals with obesity

    , Article Tehran University Medical Journal ; Volume 69, Issue 2 , 2011 , Pages 125-135 ; 16831764 (ISSN) Gholipour, M ; Kordi, M ; Taghikhani, M ; Ravasi, A ; Gaeini, A ; Tabrizi, A ; Sharif University of Technology
    Abstract
    Background: Body weight is regulated by both food intake and energy expenditure. Ghrelin, a hormone produced by the stomach and pancreas, enhances appetite. This study was undertaken to determine the effects of intermittent treadmill running on acylated ghrelin and appetite in individuals with obesity. Methods: Nine inactive male students, with a mean age of 20.56±0.48 yrs, a body mass index of 32.68±0.84 kg/m2 and a maximum oxygen uptake of 34.21±1.48 ml/kg/min, participated in the study in two trials (control and exercise) in a counterbalanced, randomized design. The protocol included intermittent running with a constant intensity at 65% of VO2 max on a treadmill. Blood samples were... 

    A systematic review of the effect of foot orthoses and shoe characteristics on balance in healthy older subjects

    , Article Prosthetics and Orthotics International ; Volume 40, Issue 2 , 2016 , Pages 170-181 ; 03093646 (ISSN) Aboutorabi, A ; Bahramizadeh, M ; Arazpour, M ; Fadayevatan, R ; Farahmand, F ; Curran, S ; Hutchins, S. W ; Sharif University of Technology
    SAGE Publications Inc  2016
    Abstract
    Background: Foot orthoses are used to optimize lower extremity function and can improve postural stability by enhancing the afferent somatosensory feedback available to the central nervous system. Objective: The aim of this review was to evaluate the effect of foot orthoses on balance control in older subjects. Study design: Systematic review. Methods: The search strategy was based on the Population Intervention Comparison Outcome method. A search was performed in PubMed, Science Direct, Google Scholar, and ISI Web of Knowledge databases by using selected keywords. A total of 22 articles were selected for final evaluation. Results: The results demonstrated that older people should be advised... 

    Effects of lumbosacral orthosis on dynamical structure of center of pressure fluctuations in patients with non-specific chronic low back pain: A randomized controlled trial

    , Article Journal of Bodywork and Movement Therapies ; Volume 23, Issue 4 , 2019 , Pages 930-936 ; 13608592 (ISSN) Azadinia, F ; Ebrahimi Takamjani, I ; Kamyab, M ; Asgari, M ; Parnianpour, M ; Sharif University of Technology
    Churchill Livingstone  2019
    Abstract
    Background: A few clinical trials have examined the effect of treatment interventions on postural control in patients with chronic low back pain, all of which have exclusively evaluated postural stability using traditional linear measures of postural sway. However, postural control improvement cannot be determined by exclusively relying on linear measurements, because these parameters provide no information on underlying motor control mechanisms. Objective: This study aimed to compare the effect of using lumbosacral orthoses (LSO) together with routine physical therapy, compared to routine physical therapy alone on postural control, using nonlinear analysis techniques. Methods: Forty-four... 

    Prevention of gestational diabetes mellitus (GDM) and probiotics: Mechanism of action: A review

    , Article Current Diabetes Reviews ; Volume 16, Issue 6 , 2020 , Pages 538-545 Homayouni, A ; Bagheri, N ; Mohammad Alizadeh Charandabi, S ; Kashani, N ; Mobaraki Asl, N ; Mirghafurvand, M ; Asgharian, H ; Ansari, F ; Pourjafar, H ; Sharif University of Technology
    Bentham Science Publishers  2020
    Abstract
    Background: Gestational Diabetes Mellitus (GDM) is a health problem that is increasing around the world. Introduction: Prevention of GDM, rather than treatment, could have several benefits in terms of both health and economic cost. Even a slight reduction in maternal glucose in non-diabetic women, particularly in women at high risk for GDM, may have significant benefits for pregnancy results and the future health of off-springs. Probiotics are a relatively new intervention, which are assessed by mothers’ metabolism, and can reduce blood sugar levels, prevent gestational diabetes and reduce the maternal and fetal complications resulting from it. The aim of this study was to review the studies... 

    The effect of magnesium supplementation on anthropometric indices: A systematic review and dose-response meta-analysis of clinical trials

    , Article British Journal of Nutrition ; Volume 125, Issue 6 , 2021 , Pages 644-656 ; 00071145 (ISSN) Rafiee, M ; Ghavami, A ; Rashidian, A ; Hadi, A ; Askari, G ; Sharif University of Technology
    Cambridge University Press  2021
    Abstract
    Abstract The aim of this study was to determine the effects of Mg supplementation on anthropometric indices consisting of body weight, waist circumference (WC), BMI and body fat percentage. In this systematic review and dose-response meta-analysis, we searched PubMed, Cochrane Library, Scopus, Web of Science and Google Scholar from databases inception up to February 2020 for relevant randomised controlled trials. Quality of evidence was evaluated using the Cochrane Collaboration Tool. All the outcomes of this meta-analysis were pooled using the random effect model. Analysis of dose-response for Mg dosage was carried out using a fractional polynomial model. The systematic review and... 

    Evaluating a new verbal working memory-balance program: a double-blind, randomized controlled trial study on Iranian children with dyslexia

    , Article BMC Neuroscience ; Volume 22, Issue 1 , 2021 ; 14712202 (ISSN) Ramezani, M ; Behzadipour, S ; Pourghayoomi, E ; Joghataei, M. T ; Shirazi, E ; Fawcett, A. J ; Sharif University of Technology
    BioMed Central Ltd  2021
    Abstract
    Background: It is important to improve verbal Working Memory (WM) in reading disability, as it is a key factor in learning. There are commercial verbal WM training programs, which have some short-term effects only on the verbal WM capacity, not reading. However, because of some weaknesses in current verbal WM training programs, researchers suggested designing and developing newly structured programs that particularly target educational functions such as reading skills. In the current double-blind randomized clinical trial study, we designed a new Verbal Working Memory-Balance (VWM-B) program which was carried out using a portable robotic device. The short-term effects of the VWM-B program,... 

    Low back pain in Iran: A growing need to adapt and implement evidence-based practice in developing countries

    , Article Spine ; Volume 36, Issue 10 , 2011 , Pages E638-E646 ; 03622436 (ISSN) Mousavi, S. J ; Akbari, M. E ; Mehdian, H ; Mobini, B ; Montazeri, A ; Akbarnia, B ; Parnianpour, M ; Sharif University of Technology
    2011
    Abstract
    Study Design.: A descriptive overview of the literature. Objective.: To present a comprehensive descriptive overview of the published papers about epidemiologic features, burden, and current management of low back pain (LBP) in Iran. Summary OF Background Data.: Little is known about the epidemiology, burden, and management of LBP in developing and low- to middle-income countries, such as Iran. Methods.: A literature search was carried out using MEDLINE database to assess existing literature about prevalence, disease burden, impact, and current management of nonspecific LBP in Iran. Results.: Twenty-six articles matched inclusion criteria and included in the study. The findings related to... 

    Intralesional immunotherapy compared to cryotherapy in the treatment of warts

    , Article International Journal of Dermatology ; Volume 56, Issue 4 , 2017 , Pages 474-478 ; 00119059 (ISSN) Khozeimeh, F ; Jabbari Azad, F ; Mahboubi Oskouei, Y ; Jafari, M ; Tehranian, S ; Alizadehsani, R ; Layegh, P ; Sharif University of Technology
    Blackwell Publishing Ltd  2017
    Abstract
    Background: Warts are the most common clinical manifestation of the human papilloma-virus infection in the skin and mucous membranes. In spite of the various therapeutic modalities for nongenital skin warts, there is still no single method to be used as an approved treatment. In this study, we compared the efficacy of immunotherapy and cryotherapy on wart lesions. Methods: Sixty patients with verruca vulgaris and plantar warts were randomly divided into two groups. One group received intralesional injection of candida antigen repeated every 3 weeks until complete improvement of all warts or for a maximum of three sessions. The second group was treated by cryotherapy with liquid nitrogen for... 

    Transcranial DC stimulation modifies functional connectivity of large-scale brain networks in abstinent methamphetamine users

    , Article Brain and Behavior ; Volume 8, Issue 3 , 2018 ; 21623279 (ISSN) Shahbabaie, A ; Ebrahimpoor, M ; Hariri, A ; Nitsche, M. A ; Hatami, J ; Fatemizadeh, E ; Oghabian, M. A ; Ekhtiari, H ; Sharif University of Technology
    John Wiley and Sons Ltd  2018
    Abstract
    Background: Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation tool suited to alter cortical excitability and activity via the application of weak direct electrical currents. An increasing number of studies in the addiction literature suggests that tDCS modulates subjective self-reported craving through stimulation of dorsolateral prefrontal cortex (DLPFC). The major goal of this study was to explore effects of bilateral DLPFC stimulation on resting state networks (RSNs) in association with drug craving modulation. We targeted three large-scale RSNs; the default mode network (DMN), the executive control network (ECN), and the salience network (SN). Methods:... 

    A pilot study of the effect of phospholipid curcumin on serum metabolomic profile in patients with non-alcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial

    , Article European Journal of Clinical Nutrition ; Volume 73, Issue 9 , 2019 , Pages 1224-1235 ; 09543007 (ISSN) Chashmniam, S ; Mirhafez, S. R ; Dehabeh, M ; Hariri, M ; Azimi Nezhad, M ; Nobakht M. Gh, B. F ; Sharif University of Technology
    Nature Publishing Group  2019
    Abstract
    Background/Objectives: Curcumin, a natural polyphenol compound in the spice turmeric, has been found to have potent anti-oxidative and anti-inflammatory activity. Curcumin may treat non-alcoholic fatty liver disease (NAFLD) through its beneficial effects on biomarkers of oxidative stress (OS) and inflammation, which are considered as two feature of this disease. However, the effects of curcumin on NAFLD have been remained poorly understood. This investigation evaluated the effects of administrating curcumin on metabolic status in NAFLD patients. Subjects/Methods: Fifty-eight NAFLD patients participated in a randomized, double-blind, placebo-controlled parallel design of study. The subjects... 

    An expert system for selecting wart treatment method

    , Article Computers in Biology and Medicine ; Volume 81 , 2017 , Pages 167-175 ; 00104825 (ISSN) Khozeimeh, F ; Alizadehsani, R ; Roshanzamir, M ; Khosravi, A ; Layegh, P ; Nahavandi, S ; Sharif University of Technology
    Elsevier Ltd  2017
    Abstract
    As benign tumors, warts are made through the mediation of Human Papillomavirus (HPV) and may grow on all parts of body, especially hands and feet. There are several treatment methods for this illness. However, none of them can heal all patients. Consequently, physicians are looking for more effective and customized treatments for each patient. They are endeavoring to discover which treatments have better impacts on a particular patient. The aim of this study is to identify the appropriate treatment for two common types of warts (plantar and common) and to predict the responses of two of the best methods (immunotherapy and cryotherapy) to the treatment. As an original work, the study was... 

    Improvement of upper limb motor control and function after competitive and noncompetitive volleyball exercises in chronic stroke survivors: a randomized clinical trial

    , Article Archives of Physical Medicine and Rehabilitation ; Volume 100, Issue 3 , 2019 , Pages 401-411 ; 00039993 (ISSN) Mandehgary Najafabadi, M ; Azad, A ; Mehdizadeh, H ; Behzadipour, S ; Fakhar, M ; Taghavi Azar Sharabiani, P ; Parnianpour, M ; Taghizadeh, G ; Khalaf, K ; Sharif University of Technology
    W.B. Saunders  2019
    Abstract
    Objectives: To investigate the effects of competitive and noncompetitive volleyball exercises on the functional performance and motor control of the upper limbs in chronic stroke survivors. Design: Randomized clinical trial. Setting: Outpatient rehabilitation center. Participants: Chronic stroke survivors (N=48). Interventions: Participants were randomly assigned to competitive (n=16) or noncompetitive (n=16) volleyball exercise groups (60min/d volleyball exercise+30min/d traditional rehabilitation, 3d/wk for 7wk) and control group (n=16). Main Outcome Measures: Reach and grasp motor control measures were evaluated through kinematic analysis. Functional outcomes were assessed via Motor... 

    Challenges and future prospects for the delivery of biologics: oral mucosal, pulmonary, and transdermal routes

    , Article AAPS Journal ; Volume 19, Issue 3 , 2017 , Pages 652-668 ; 15507416 (ISSN) Morales, J. O ; Fathe, K. R ; Brunaugh, A ; Ferrati, S ; Li, S ; Montenegro Nicolini, M ; Mousavikhamene, Z ; McConville, J. T ; Prausnitz, M. R ; Smyth, H. D. C ; Sharif University of Technology
    Springer New York LLC  2017
    Abstract
    Biologic products are large molecules such as proteins, peptides, nucleic acids, etc., which have already produced many new drugs for clinical use in the last decades. Due to the inherent challenges faced by biologics after oral administration (e.g., acidic stomach pH, digestive enzymes, and limited permeation through the gastrointestinal tract), several alternative routes of administration have been investigated to enable sufficient drug absorption into systemic circulation. This review describes the buccal, sublingual, pulmonary, and transdermal routes of administration for biologics with relevant details of the respective barriers. While all these routes avoid transit through the...