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    Stockwell transform for epileptic seizure detection from EEG signals

    , Article Biomedical Signal Processing and Control ; Volume 38 , 2017 , Pages 108-118 ; 17468094 (ISSN) Kalbkhani, H ; Shayesteh, M. G ; Sharif University of Technology
    Epilepsy is the most common disorder of human brain. The goal of this paper is to present a new method for classification of epileptic phases based on the sub-bands of electroencephalogram (EEG) signals obtained from the Stockwell transform (ST). ST is a time-frequency analysis that not only covers the advantages of both short-time Fourier transform (FT) and wavelet transform (WT), but also overcomes their shortcomings. In the proposed method, at first, EEG signal is transformed into time-frequency domain using ST and all operations are performed in the new domain. Then, the amplitudes of ST in five sub-bands, namely delta (δ), theta (θ), alpha (α), beta (β), and gamma (γ), are computed. In... 

    Investigation of the modulation between EEG alpha waves and slow/fast delta waves in children in different depths of Desflurane anesthesia

    , Article IRBM ; Volume 31, Issue 1 , 2010 , Pages 55-66 ; 19590318 (ISSN) Molaee Ardekani, B ; Shamsollahi, M. B ; Tirel, O ; Vosoughi Vahdat, B ; Wodey, E ; Senhadji, L ; Sharif University of Technology
    Objectives: Investigation of the amplitude modulation of alpha-band EEG oscillations (i.e., grouping of alpha-band activities) by delta-band EEG activities in various depths of anesthesia (DOA). Methods: This modulation, which is a sort of phase dependent amplitude modulation, is studied in 10 children in various depths of Desflurane anesthesia. Two parameters are defined to quantify the modulation: strength of modulation (SOM) and phase of modulation (POM). SOM indicates to what extent delta and alpha activities are related to each other, and POM is the delta phase in which the alpha amplitude is maximal. These parameters are analyzed in different DOA for various formations of delta... 

    Lumbopelvic Rhythm during Forward and Backward Sagittal Trunk Rotations; in vivo Measurements Using Inertial Sensors

    , M.Sc. Thesis Sharif University of Technology Tafazzol, Alireza (Author) ; Arjmand, Navid (Supervisor)
    Direct in vivo measurements of spinal loads and muscle forces are invasive. Investigators have thus used musculoskeletal biomechanical models that require kinematic data including trunk and pelvis angular movements as their inputs. . Novel devices measure anglular movements using both inertial sensors (such as gyroscopes and accelerometers) and miniature magnetometers. Relative low cost, portability, and accuracy are among specific characteristics of inertial tracking devices. The main objective of the present study was set to measure spinal kinematics including the lumbopelvic rhythm as the ratio of total lumbar rotation over pelvic rotation during trunk sagittal movement which is essential... 

    3D Spinal Kinematics During Load-Handling Activities, Range of Motions and Movement Coordination in Normal and Obese Individuals

    , M.Sc. Thesis Sharif University of Technology Ghasemi Varnamkhasti, Morteza (Author) ; Arjmand, Navid (Supervisor)
    Today, obesity, as a major global health challenge, affects more than 30 percent of the world's population. To investigate the effect of obesity on spinal function, a common method is motion analysis (kinematic method). This method is based on the claim that the abnormal mechanical function of the spine is directly related to its abnormal motions.The aim of this study is to measure and compare the range of motions (RoMs) of different segments of the spine in all anatomical plates between obese and normal individuals, as well as to calculate and compare some motion rhythms between the lumbar spine and the pelvis in these two groups. Comparing the posture of the spine between obese and normal... 

    Lumbopelvic rhythm during forward and backward sagittal trunk rotations: Combined in vivo measurement with inertial tracking device and biomechanical modeling

    , Article Clinical Biomechanics ; Vol. 29, issue. 1 , 2014 , pp. 7-13 ; ISSN: 02680033 Tafazzol, A ; Arjmand, N ; Shirazi-Adl, A ; Parnianpour, M ; Sharif University of Technology
    Background The ratio of total lumbar rotation over pelvic rotation (lumbopelvic rhythm) during trunk sagittal movement is essential to evaluate spinal loads and discriminate between low back pain and asymptomatic population. Methods Angular rotations of the pelvis and lumbar spine as well as their sagittal rhythm during forward flexion and backward extension in upright standing of eight asymptomatic males are measured using an inertial tracking device. The effect of variations in the lumbopelvic ratio during trunk flexion on spinal loads is quantified using a detailed musculoskeletal model. Findings The mean of peak voluntary flexion rotations of the thorax, pelvis, and lumbar was 121 (SD... 

    Delta waves differently modulate high frequency components of EEG oscillations in various unconsciousness levels

    , Article 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07, Lyon, 23 August 2007 through 26 August 2007 ; 2007 , Pages 1294-1297 ; 05891019 (ISSN); 1424407885 (ISBN); 9781424407880 (ISBN) Molaee Ardekani, B ; Senhadji, L ; Shamsollahi, M. B ; Wodey, E ; Vosoughi Vahdat, B ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2007
    In this paper we investigate the modulation properties of high frequency EEG activities by delta waves during various depth of anesthesia. We show that slow and fast delta waves (0-2 Hz and 2-4 Hz respectively) and high frequency components of the EEG (8-20 Hz) are correlated with each other and there is a kind of phase locking between them that varies with depth of anesthesia. Our analyses show that maximum amplitudes of high frequency components of the EEG signal are appeared in different phases of slow and fast delta waves when the concentration of Desflurane and Propofol anesthetic agents varies in a patient. There are some slight differences in using slow and fast components of delta... 

    Allergic rhinitis impairs working memory in association with drop of hippocampal – Prefrontal coupling

    , Article Brain Research ; Volume 1758 , 2021 ; 00068993 (ISSN) Salimi, M ; Ghazvineh, S ; Nazari, M ; Dehdar, K ; Garousi, M ; Zare, M ; Tabasi, F ; Jamaati, H ; Salimi, A ; Barkley, V ; Mirnajafi Zadeh, J ; Raoufy, M. R ; Sharif University of Technology
    Elsevier B.V  2021
    Allergic rhinitis (AR) is a chronic inflammatory disease frequently associated with a deficit in learning and memory. Working memory is an important system for decision making and guidance, which depends on interactions between the ventral hippocampus (vHipp) and the prelimbic prefrontal cortex (plPFC). It is still unclear whether AR influences the activity and coupling of these brain areas, which consequently may impair working memory. The current study aimed to examine alterations of the vHipp-plPFC circuit in a rat model of AR. Our results show decreased working memory performance in AR animals, accompanied by a reduction of theta and gamma oscillations in plPFC. Also, AR reduces... 

    Dynamic comparison of segmentary scapulohumeral rhythm between athletes with and without impingement syndrome

    , Article Iranian Journal of Radiology ; Vol. 11, issue. 2 , 2014 Taghizadeh Delkhoush, C ; Maroufi, N ; Ebrahimi Takamjani, I ; Farahmand, F ; Shakourirad, A ; Haghani, H ; Sharif University of Technology
    Background: Patients who have shoulder pain usually have compensatory or contributory deviation of shoulder motion during arm elevation. In the traditional scapulohumeral rhythm, the share of the acromioclavicular (AC) and the sternoclavicular (SC) joint movements and also the role of AC internal rotation angle are unknown. Objectives: The main purpose of this study was to measure and compare the segmentary scapulohumeral rhythm (SSHR) during scapular arm elevation at a steady rotational speed in athletes with and without impingement syndrome. Patients and Methods: Using a speedometer, the maximum speed of arm elevation was measured in 21 men in each of the involved and uninvolved groups.... 

    ECG denoising using angular velocity as a state and an observation in an Extended Kalman Filter framework

    , Article Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS ; 2012 , Pages 2897-2900 ; 1557170X (ISSN) ; 9781424441198 (ISBN) Akhbari, M ; Shamsollahi, M. B ; Jutten, C ; Coppa, B ; Sharif University of Technology
    In this paper an efficient filtering procedure based on Extended Kalman Filter (EKF) has been proposed. The method is based on a modified nonlinear dynamic model, previously introduced for the generation of synthetic ECG signals. The proposed method considers the angular velocity of ECG signal, as one of the states of an EKF. We have considered two cases for observation equations, in one case we have assumed a corresponding observation to angular velocity state and in the other case, we have not assumed any observations for it. Quantitative evaluation of the proposed algorithm on the MIT-BIH Normal Sinus Rhythm Database (NSRDB) shows that an average SNR improvement of 8 dB is achieved for an... 

    Synchronizing hindmarsh-rose neurons over newman-watts networks

    , Article Chaos ; Volume 19, Issue 3 , 2009 ; 10541500 (ISSN) Jalili, M ; Sharif University of Technology
    American Institute of Physics Inc  2009
    In this paper, the synchronization behavior of the Hindmarsh-Rose neuron model over Newman-Watts networks is investigated. The uniform synchronizing coupling strength is determined through both numerically solving the network's differential equations and the master-stability-function method. As the average degree is increased, the gap between the global synchronizing coupling strength, i.e., the one obtained through the numerical analysis, and the strength necessary for the local stability of the synchronization manifold, i.e., the one obtained through the master-stability-function approach, increases. We also find that this gap is independent of network size, at least in a class of networks... 

    Properties of functional brain networks correlate frequency of psychogenic non-epileptic seizures

    , Article Frontiers in Human Neuroscience ; Issue DEC , 2012 ; 16625161 (ISSN) Barzegaran, E ; Joudaki, A ; Jalili, M ; Rossetti, A. O ; Frackowiak, R. S ; Knyazeva, M. G ; Sharif University of Technology
    Frontiers Media S. A  2012
    Abnormalities in the topology of brain networks may be an important feature and etiological factor for psychogenic non-epileptic seizures (PNES). To explore this possibility, we applied a graph theoretical approach to functional networks based on resting state EEGs from 13 PNES patients and 13 age- and gender-matched controls. The networks were extracted from Laplacian-transformed time-series by a cross-correlation method. PNES patients showed close to normal local and global connectivity and small-world structure, estimated with clustering coefficient, modularity, global efficiency, and small-worldness metrics, respectively. Yet the number of PNES attacks per month correlated with a... 

    A combined dynamical sequential network for generating coupled cardiovascular signals with different beat types

    , Article ; 2010 3rd International Symposium on Applied Sciences in Biomedical and Communication Technologies, ISABEL 2010, 7 November 2010 through 10 November 2010 , 2010 ; 9781424481323 (ISBN) Sayadi, O ; Shamsollahi, M. B ; Sharif University of Technology
    We present generalizations of the previously published artificial models for generating abnormal cardiac rhythms to provide simulations of coupled cardiovascular (CV) signals with different beat morphologies. Using a joint dynamical formulation, we generate the normal morphologies of the cardiac cycle using a sum of Gaussian kernels, fitted to real CV recordings. The joint inter-dependencies of CV signals are introduced by assuming the same angular frequency and a phase coupling. Abnormal beats are then specified as new dynamical trajectories. An ergadic first-order Markov chain is also used for switching between normal and abnormal beat types. Probability transitions can be learned from... 

    Efficient embedding of empirically-derived constraints in the ODE formulation of multibody systems: Application to the human body musculoskeletal system

    , Article Mechanism and Machine Theory ; Volume 133 , 2019 , Pages 673-690 ; 0094114X (ISSN) Ehsani, H ; Poursina, M ; Rostami, M ; Mousavi, A ; Parnianpour, M ; Khalaf, K ; Sharif University of Technology
    Elsevier Ltd  2019
    We present a novel method for deriving the governing equations of the musculoskeletal system, a new class of multibody systems in which the constituent components are connected together via anatomical joints which behave differently compared with traditional mechanical joints. In such systems, the kinematics of the joints and the corresponding constraints are characterized experimentally. We generate the equations of motion of these complex systems in which the homogeneous transformation matrices become matrix-valued functions of the generalized coordinate vector due to the empirical expression of body coordinates as smooth functions of generalized coordinates. The detailed mathematical... 

    Spinal segment ranges of motion, movement coordination, and three-dimensional kinematics during occupational activities in normal-weight and obese individuals

    , Article Journal of Biomechanics ; Volume 123 , 2021 ; 00219290 (ISSN) Ghasemi, M ; Arjmand, N ; Sharif University of Technology
    Elsevier Ltd  2021
    Measurements of spinal segment ranges of motion (RoMs), movement coordination, and three-dimensional kinematics during occupational activities have implications in occupational/clinical biomechanics. Due to the large amount of adipose tissues, obese individuals may have different RoMs, lumbopelvic coordination, and kinematics than normal-weight ones. We aimed to measure/compare trunk, lumbar, and pelvis primary RoMs in all anatomical planes/directions, lumbopelvic ratios (lumbar to pelvis rotations at different trunk angles) in all anatomical planes/directions and three-dimensional spine kinematics during twelve symmetric/asymmetric statics load-handling activities in healthy normal-weight... 

    Substrate oscillations boost recombinant protein release from Escherichia coli

    , Article Bioprocess and Biosystems Engineering ; Volume 37, Issue 5 , May , 2014 , Pages 881-890 ; ISSN: 16157591 Jazini, M ; Herwig, C ; Sharif University of Technology
    Intracellular production of recombinant proteins in prokaryotes necessitates subsequent disruption of cells for protein recovery. Since the cell disruption and subsequent purification steps largely contribute to the total production cost, scalable tools for protein release into the extracellular space is of utmost importance. Although there are several ways for enhancing protein release, changing culture conditions is rather a simple and scalable approach compared to, for example, molecular cell design. This contribution aimed at quantitatively studying process technological means to boost protein release of a periplasmatic recombinant protein (alkaline phosphatase) from E. coli.... 

    Digital implementation of a biological astrocyte model and its application

    , Article IEEE Transactions on Neural Networks and Learning Systems ; Volume 26, Issue 1 , 2014 , Pages 127-139 ; 2162237X (ISSN) Soleimani, H ; Bavandpour, M ; Ahmadi, A ; Abbott, D ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2014
    This paper presents a modified astrocyte model that allows a convenient digital implementation. This model is aimed at reproducing relevant biological astrocyte behaviors, which provide appropriate feedback control in regulating neuronal activities in the central nervous system. Accordingly, we investigate the feasibility of a digital implementation for a single astrocyte and a biological neuronal network model constructed by connecting two limit-cycle Hopf oscillators to an implementation of the proposed astrocyte model using oscillator-astrocyte interactions with weak coupling. Hardware synthesis, physical implementation on field-programmable gate array, and theoretical analysis confirm... 

    A three-dimensional statistical volume element for histology informed micromechanical modeling of brain white matter

    , Article Annals of Biomedical Engineering ; Volume 48, Issue 4 , 2020 , Pages 1337-1353 Hoursan, H ; Farahmand, F ; Ahmadian, M. T ; Sharif University of Technology
    Springer  2020
    This study presents a novel statistical volume element (SVE) for micromechanical modeling of the white matter structures, with histology-informed randomized distribution of axonal tracts within the extracellular matrix. The model was constructed based on the probability distribution functions obtained from the results of diffusion tensor imaging as well as the histological observations of scanning electron micrograph, at two structures of white matter susceptible to traumatic brain injury, i.e. corpus callosum and corona radiata. A simplistic representative volume element (RVE) with symmetrical arrangement of fully alligned axonal fibers was also created as a reference for comparison. A... 

    Neuromuscular control of the point to point and oscillatory movements of a sagittal arm with the actor-critic reinforcement learning method

    , Article Computer Methods in Biomechanics and Biomedical Engineering ; Volume 8, Issue 2 , 2005 , Pages 103-113 ; 10255842 (ISSN) Golkhou, V ; Parnianpour, M ; Lucas, C ; Sharif University of Technology
    In this study, we have used a single link system with a pair of muscles that are excited with alpha and gamma signals to achieve both point to point and oscillatory movements with variable amplitude and frequency. The system is highly nonlinear in all its physical and physiological attributes. The major physiological characteristics of this system are simultaneous activation of a pair of nonlinear musclelike- actuators for control purposes, existence of nonlinear spindle-like sensors and Golgi tendon organlike sensor, actions of gravity and external loading. Transmission delays are included in the afferent and efferent neural paths to account for a more accurate representation of the reflex...