Sharif Digital Repository

The growth of process industries has escalated the probability of loss containment scenarios of hazardous materials that can be tackled via process safety schemes. For preliminary design stage, the inherent scheme is more promising to generate sustainable process designs. For this purpose, various process routes are typically compared to recognize the safer one via numerous indexing methods to eliminate routes with hazardous materials. However, these indices lack in accommodating the equipment characteristics and the underutilization of process and chemical characteristics. Specifically for chemical characteristics, the toxicity aspect has not been engaged for process route selection in...