Loading...
Search for:
scaffold-fabrication
0.004 seconds
Mechanical reinforcement of urinary bladder matrix by electrospun polycaprolactone nanofibers
, Article Scientia Iranica ; Volume 24, Issue 6 , 2017 , Pages 3476-3480 ; 10263098 (ISSN) ; Rajabi Zeleti, S ; Naji, M ; Ghanian, M. H ; Baharvand, H ; Sharif University of Technology
Abstract
For a successful repair and reconstruction of bladder tissue, fabrication of scaffolds with proper biochemical and biomechanical characteristics is necessary. Decellularized bladder tissue has been proposed in previous studies as a gold standard material for scaffold fabrication. However, weak mechanical properties of such a load-bearing tissue has remained a challenge. Incorporation of both biological and synthetic materials has been known as an effective strategy for improving mechanical and biological properties of the scaffolds. In the present work, a simple process was developed to fabricate hybrid hydrogel scaffolds with a biomimetic architecture from the natural urinary bladder...
Evaluation of cellular attachment and proliferation on different surface charged functional cellulose electrospun nanofibers
, Article Carbohydrate Polymers ; Volume 207 , 2019 , Pages 796-805 ; 01448617 (ISSN) ; Karimi, A ; Gandomi Ravandi, S ; Vossoughi, M ; Khafaji, M ; Joghataei, M. T ; Faghihi, F ; Sharif University of Technology
Elsevier Ltd
2019
Abstract
Fabrication and characterization of different surface charged cellulose electrospun scaffolds including cellulose acetate (CA), cellulose, carboxymethyl cellulose (CMC) and quaternary ammonium cationic cellulose (QACC) for biomedical applications have been reported in this research. Several instrumental techniques were employed to characterize the nanofibers. MTT assay and cell attachment studies were also carried out to determine the cytocompatibility, viability and proliferation of the scaffolds. Fabricated CA, cellulose, CMC and QACC nanofibers had 100–600 nm diameter, −9, −1.75, −12.8, + 22 mV surface potential, 2.5, 4.2, 7.2, 7 MPa tensile strength, 122, 320, 515, 482 MPa Young modules,...