Loading...
Search for:
small-animal-imaging
0.01 seconds
Implementation of absolute quantification in small-animal SPECT imaging: Phantom and animal studies
, Article Journal of Applied Clinical Medical Physics ; Volume 18, Issue 4 , 2017 , Pages 215-223 ; 15269914 (ISSN) ; Vosoughi, N ; Tanha, K ; Assadi, M ; Ghafarian, P ; Rahmim, A ; Ay, M. R
John Wiley and Sons Ltd
2017
Abstract
Purpose: Presence of photon attenuation severely challenges quantitative accuracy in single-photon emission computed tomography (SPECT) imaging. Subsequently, various attenuation correction methods have been developed to compensate for this degradation. The present study aims to implement an attenuation correction method and then to evaluate quantification accuracy of attenuation correction in small-animal SPECT imaging. Methods: Images were reconstructed using an iterative reconstruction method based on the maximum-likelihood expectation maximization (MLEM) algorithm including resolution recovery. This was implemented in our designed dedicated small-animal SPECT (HiReSPECT) system. For...
Study of two-layer tapered depth of interaction PET detector
, Article Applied Radiation and Isotopes ; Volume 174 , 2021 ; 09698043 (ISSN) ; Yousefnejad, S ; Shafiee, M ; Rafiei, A ; Sharif University of Technology
Elsevier Ltd
2021
Abstract
Improving detection efficiency in small animal PET scanners without degrading spatial resolution is one of the main problems of these scanners. Commercial small animal PET scanners use different methods to achieve desirable levels of sensitivity and spatial resolution. GE Healthcare eXplore VISTA PET scanner uses double layer (LYSO-GSO) depth-of-interaction (DOI) capable cuboid detector modules. In this work, the design of GE Healthcare eXplore VISTA PET scanner is improved using tapered detector geometry instead of cuboid geometry. Using tapered detector geometry, the gaps between adjacent modules are filled and the sensitive volume has increased about 11.5%. The new designed PET scanner...