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    Metabolomics fingerprinting of the human seminal plasma of asthenozoospermic patients

    , Article Molecular Reproduction and Development ; Vol. 81, Issue. 1 , 2014 , pp. 84-86 ; ISSN: 1098-2795 Gilany, K ; Moazeni-Pourasil, R. S ; Jafarzadeh, N ; Savadi-Shiraz, E ; Sharif University of Technology
    Abstract
    It is estimated that 20% of couples are infertile, and half of these infertility cases are linked to men. One of conditions that can affect male fertility is asthenozoospermia. We applied Raman spectroscopy to the analysis of the metabolome of the human seminal plasma, and used chemometrics on the patterns of Raman spectra obtained. Significant changes were observed in the metabolome of the human seminal plasma of asthenozoospermic patients