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    Comparison of periodontally compromised splinted teeth and implant supported fixed partial denture: a three-dimensional finite element analysis on bone response

    , Article Journal of long-term effects of medical implants ; Volume 31, Issue 2 , 2021 , Pages 1-8 ; 19404379 (ISSN) Amid, R ; Kadkhodazadeh, M ; Talebi Ardakani, M. R ; Movahhedy, M. R ; Mirakhori, M ; Hakimi, A ; Broukhim, M ; Sharif University of Technology
    NLM (Medline)  2021
    Abstract
    Introduction - This study aimed to compare the amount and pattern of stress and strain distributed around periodontally compromised splinted teeth and the two-implant abutments supported six-unit fixed partial denture (FPD) using finite element analysis (FEA). Methods and Materials - Six mandibular anterior teeth of a dental model were scanned and the scans were transferred to 3D CAD design and finite element software. Jaw bone was also designed and the teeth were splinted by fiber-reinforced composite (FRC) band. In another model, two implants were placed at the site of canine teeth and a six-unit FPD was designed over them. Models were transferred to finite element software and after... 

    Stretching an anisotropic DNA

    , Article Journal of Chemical Physics ; Volume 128, Issue 12 , 2008 ; 00219606 (ISSN) Eslami Mossallam, B ; Ejtehadi, M. R ; Sharif University of Technology
    2008
    Abstract
    We present a perturbation theory to find the response of an anisotropic DNA to the external tension. It is shown that the anisotropy has a nonzero but small contribution to the force-extension curve of the DNA. Thus an anisotropic DNA behaves like an isotropic one with an effective bending constant equal to the harmonic average of its soft and hard bending constants. © 2008 American Institute of Physics  

    Nanoindentation of isotactic polypropylene: Correlations between hardness, yield stress, and modulus on the local and global scales

    , Article Journal of Applied Polymer Science ; Volume 121, Issue 2 , February , 2011 , Pages 930-938 ; 00218995 (ISSN) Lesan Khosh, R ; Bagheri, R ; Asgari, S ; Sharif University of Technology
    2011
    Abstract
    The correlations between the hardness, yield stress, and modulus of elasticity of isotactic polypropylene (iPP) were evaluated on the local and global scales. Nanoindentation and traditional macromechanical tests were incorporated for this purpose. Thus, local and global mechanical properties were measured at various temperatures and strain rates. A certain relation was found between the local and global mechanical properties. Moreover, Johnson's model (developed according to the expanding cavity model) was also evaluated at various temperatures and strain rates. The Johnson model was valid only for the yield stresses obtained by nanoindentation and compressive tests and also the elastic... 

    Properties of Nafion Under Uniaxial Loading at Different Temperatures: A Molecular Dynamics Study

    , Article Polymer - Plastics Technology and Engineering ; Volume 54, Issue 8 , 2015 , Pages 806-813 ; 03602559 (ISSN) Ozmaian, M ; Naghdabadi, R ; Sharif University of Technology
    Taylor and Francis Inc  2015
    Abstract
    Nafion membrane encounters many different thermal conditions and mechanical loadings because of its wide range of applications as a proton exchange membrane (PEM). Molecular dynamics simulation of hydrated Nafion at different temperatures is carried out to investigate the alteration of the physical properties of Nafion under uniaxial loading over a wide range of temperatures. According to the simulation results, increase of the temperature reduces the yield stress. The results also show that the polymer chains ordering increases the glass transition temperature and enhances the self-diffusion coefficient of water in hydrated Nafion. Comparisons show that the elastic modulus and viscosity... 

    On the evolution of flow stress during constrained groove pressing of pure copper sheet

    , Article Computational Materials Science ; Volume 45, Issue 4 , 2009 , Pages 855-859 ; 09270256 (ISSN) Hosseini, E ; Kazeminezhad, M ; Mani, A ; Rafizadeh, E ; Sharif University of Technology
    2009
    Abstract
    Using a mechanical model and dislocation density based model, the evolutions of dislocation density and flow stress of pure copper during constrained groove pressing (CGP) process are investigated. In this regard, the strain and strain rate are achieved from the mechanical model and then input into the dislocation model. To verify the predicted flow stress, the process of constrained groove pressing is performed on the sheets of pure copper from one to three passes. The predicted flow stresses are compared with the experimental data and a good agreement is observed. Also, it is found that during the straining of the copper sheet in CGP process, the dislocation density and strength dropping... 

    A viscoelastic model for axonal microtubule rupture

    , Article Journal of Biomechanics ; Volume 48, Issue 7 , 2015 , Pages 1241-1247 ; 00219290 (ISSN) Shamloo, A ; Manuchehrfar, F ; Rafii Tabar, H ; Sharif University of Technology
    Elsevier Ltd  2015
    Abstract
    Axon is an important part of the neuronal cells and axonal microtubules are bundles in axons. In axons, microtubules are coated with microtubule-associated protein tau, a natively unfolded filamentous protein in the central nervous system. These proteins are responsible for cross-linking axonal microtubule bundles. Through complimentary dimerization with other tau proteins, bridges are formed between nearby microtubules creating bundles. Formation of bundles of microtubules causes their transverse reinforcement and has been shown to enhance their ability to bear compressive loads. Though microtubules are conventionally regarded as bearing compressive loads, in certain circumstances during... 

    Analysis of different material theories used in a FE model of a lumbar segment motion

    , Article Acta of Bioengineering and Biomechanics ; Volume 15, Issue 2 , 2013 , Pages 33-41 ; 1509409X (ISSN) Gohari, E ; Nikkhoo, M ; Haghpanahi, M ; Parnianpour, M ; Sharif University of Technology
    2013
    Abstract
    In this study, a nonlinear poroelastic model of intervertebral disc as an infrastructure was developed. Moreover, a new element was defined consisting a disc (Viscoelastic Euler Beam Element) and a vertebra (Rigid Link) as a unit element. Using the new element, three different viscoelastic finite element models were prepared for lumbar motion segment (L4/L5). Prolonged loading (short-term and long-term creep) and cyclic loading were applied to the models and the results were compared with results of in vivo tests. Simplification of the models by using the new element leads to reduction of the runtime of the models in dynamic analyses to few minutes without losing the accuracy in the results  

    Tool-tissue force estimation in laparoscopic surgery using geometric features

    , Article Studies in Health Technology and Informatics ; Volume 184 , 2013 , Pages 225-229 ; 09269630 (ISSN) Kohani, M ; Behzadipour, S ; Farahmand, F ; Sharif University of Technology
    IOS Press  2013
    Abstract
    This paper introduces three geometric features, from deformed shape of a soft tissue, which demonstrate good correlation with probing force and maximum local stress. Using FEM simulation, 2D and 3D model of an in vivo porcine liver was built for different probing tasks. Maximum deformation angle, maximum deformation depth and width of displacement constraint of the reconstructed shape of the deformed body were calculated. Two neural networks were trained from these features and the calculated interaction forces. The features are shown to have high potential to provide force estimation either for haptic devices or to assess the damage to the tissue in large deformations of up to 40%  

    A 3-D constitutive model for pressure-dependent phase transformation of porous shape memory alloys

    , Article Journal of the Mechanical Behavior of Biomedical Materials ; Volume 42 , 2015 , Pages 292-310 ; 17516161 (ISSN) Ashrafi, M. J ; Arghavani, J ; Naghdabadi, R ; Sohrabpour, S ; Sharif University of Technology
    Abstract
    Porous shape memory alloys (SMAs) exhibit the interesting characteristics of porous metals together with shape memory effect and pseudo-elasticity of SMAs that make them appropriate for biomedical applications. In this paper, a 3-D phenomenological constitutive model for the pseudo-elastic behavior and shape memory effect of porous SMAs is developed within the framework of irreversible thermodynamics. Comparing to micromechanical and computational models, the proposed model is computationally cost effective and predicts the behavior of porous SMAs under proportional and non-proportional multiaxial loadings. Considering the pressure dependency of phase transformation in porous SMAs, proper... 

    Effect of interface stresses on the elastic deformation of an elastic half-plane containing an elastic inclusion

    , Article International Journal of Solids and Structures ; Volume 46, Issue 14-15 , 2009 , Pages 2897-2906 ; 00207683 (ISSN) Avazmohammadi, R ; Yang, F ; Abbasion, S ; Sharif University of Technology
    2009
    Abstract
    The effect of the interface stresses is studied upon the size-dependent elastic deformation of an elastic half-plane having a cylindrical inclusion with distinct elastic properties. The elastic half-plane is subjected to either a uniaxial loading at infinity or a uniform non-shear eigenstrain in the inclusion. The straight edge of the half-plane is either traction-free, or rigid-slip, or motionless, which represents three practical situations of mechanical structures. Using two-dimensional Papkovich-Neuber potentials and the theory of surface/interface elasticity, the elastic field in the elastic half-plane is obtained. Comparable with classical result, the new formulation renders the... 

    A rigid body spring model to investigate the lateral shift-Restraining force behavior of the patellar

    , Article 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07, Lyon, 23 August 2007 through 26 August 2007 ; 2007 , Pages 4679-4682 ; 05891019 (ISSN) ; 1424407885 (ISBN); 9781424407880 (ISBN) Jafari, A ; Farahmand, F ; Meghdari, A ; Sharif University of Technology
    2007
    Abstract
    Patellar lateral stability was studied using a 2D transverse plane model with deformable articular surfaces. Quadriceps muscles and patellar tendon were considered as strings with predefined forces and lateral and medial retinaculum as tensile springs. Deformation behavior of articular cartilage was modeled by a set of compression springs perpendicular to articular surfaces, based on rigid body spring model method (RBSM). Patellar lateral stability was investigated using restraining force method (the external force required to cause up to 10 mm lateral displacement on patella). The results were in good agreement with experimental reports for normal joint, vastus lateralis and vastus medialis... 

    A new approach to C2 continuous piecewise bicubic representation of the articular surfaces of diarthrodial joints

    , Article Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine ; Volume 220, Issue 4 , 2006 , Pages 553-563 ; 09544119 (ISSN) Jafari, A ; Farahmand, F ; Meghdari, A ; Golestanha, A. S ; Sharif University of Technology
    2006
    Abstract
    Based on the force-deflection equation for a beam subjected to lateral point loads, a C2 continuous piecewise bicubic mathematical representation was proposed to model complicated geometrical surfaces, e.g. the articular surfaces of human joints. The method was then extended so that it could be used for mathematical modelling of incomplete nets of data points, as well as smoothing of noisy and/or filtering of erroneous data points. Mathematical techniques were also developed to calculate the required unknown parameters explicitly, with no need to solve the system of equations simultaneously. The performance of the proposed method was evaluated on a number of surface modelling problems,... 

    A multi-objective approach to optimize the weight and stress of the locking plates using finite element modeling

    , Article Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine ; Volume 236, Issue 2 , 2022 , Pages 188-198 ; 09544119 (ISSN) Rafiei, S ; Nourani, A ; Chizari, M ; Sharif University of Technology
    SAGE Publications Ltd  2022
    Abstract
    This paper aims to identify an optimum bone fracture stabilizer. For this purpose, three design variables including the ratio of the screw diameter to the plate width at three levels, the ratio of the plate thickness to the plate width at three levels, and the diameter of the bone at two levels were selected for analysis. Eighteen 3D verified finite element models were developed to examine the effects of these parameters on the weight, maximum displacement and maximum von Mises stress of the fixation structure. Considering the relations between the inputs and outputs using multivariate regression, a genetic algorithm was used to find the optimal choices. Results showed that the diameter of... 

    A meta-model analysis of a finite element simulation for defining poroelastic properties of intervertebral discs

    , Article Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine ; Volume 227, Issue 6 , 2013 , Pages 672-682 ; 09544119 (ISSN) Nikkhoo, M ; Hsu, Y. C ; Haghpanahi, M ; Parnianpour, M ; Wang, J. L ; Sharif University of Technology
    2013
    Abstract
    Finite element analysis is an effective tool to evaluate the material properties of living tissue. For an interactive optimization procedure, the finite element analysis usually needs many simulations to reach a reasonable solution. The metamodel analysis of finite element simulation can be used to reduce the computation of a structure with complex geometry or a material with composite constitutive equations. The intervertebral disc is a complex, heterogeneous, and hydrated porous structure. A poroelastic finite element model can be used to observe the fluid transferring, pressure deviation, and other properties within the disc. Defining reasonable poroelastic material properties of the... 

    An analytical approach to study the intraoperative fractures of femoral shaft during total hip arthroplasty

    , Article Journal of Biomechanical Engineering ; Volume 135, Issue 4 , 2013 ; 01480731 (ISSN) Malekmotiei, L ; Farahmand, F ; Shodja, H. M ; Samadi Dooki, A ; Sharif University of Technology
    2013
    Abstract
    An analytical approach which is popular in micromechanical studies has been extended to the solution for the interference fit problem of the femoral stem in cementless total hip arthroplasty (THA). The multiple inhomogeneity problem of THA in transverse plane, including an elliptical stem, a cortical wall, and a cancellous layer interface, was formulated using the equivalent inclusion method (EIM) to obtain the induced interference elastic fields. Results indicated a maximum interference fit of about 210 μm before bone fracture, predicted based on the Drucker-Prager criterion for a partially reamed section. The cancellous layer had a significant effect on reducing the hoop stresses in the... 

    Investigation of the effect of high +Gz accelerations on human cardiac function

    , Article Journal of the Mechanical Behavior of Biomedical Materials ; Volume 27 , 2013 , Pages 54-63 ; 17516161 (ISSN) Jamshidi, M ; Ahmadian, M. T ; Sharif University of Technology
    Abstract
    This study investigates the effect of body acceleration on human cardiac function. Finite element analysis is conducted to simulate geometrical and mechanical properties of human heart. Heart geometrical modeling in three-dimension is performed by segmentation of cardiac MRI images. The nonlinear mechanical behavior of myocardium is modeled by Mooney-Rivlin, Polynomial, Ogden and Yeoh hyperelastic material models. Stress-strain curves of myocardial tissue are obtained from experimental compression tests on bovine heart samples. The experimental results are employed for the evaluation of material coefficients by the nonlinear least squares method. Among hyperelastic models, the Yeoh model... 

    Preparation and characteristics of epoxy/clay/B4C nanocomposite at high concentration of boron carbide for neutron shielding application

    , Article Radiation Physics and Chemistry ; Volume 141 , 2017 , Pages 223-228 ; 0969806X (ISSN) Kiani, M. A ; Ahmadi, S. J ; Outokesh, M ; Adeli, R ; Mohammadi, A ; Sharif University of Technology
    Abstract
    In this research, the characteristics of the prepared samples in epoxy matrix by means of X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDS), as well as scanning electron microscope (SEM) are evaluated. Meanwhile, the obtained mechanical properties of the specimen are investigated. Thermogravimetric analysis (TGA) is also employed to evaluate the thermal degradation of manufactured nanocomposites. The thermal neutron absorption properties of nanocomposites containing 3 wt% of montmorillonite nanoclay (closite30B) have been studied experimentally, using an Am-Be point source. Mechanical tests reveal that the higher B4C concentrations, the more tensile strengths, but lower... 

    Micromechanical modeling of rate-dependent behavior of Connective tissues

    , Article Journal of Theoretical Biology ; Volume 416 , 2017 , Pages 119-128 ; 00225193 (ISSN) Fallah, A ; Ahmadian, M. T ; Firozbakhsh, K ; Aghdam, M. M ; Sharif University of Technology
    Academic Press  2017
    Abstract
    In this paper, a constitutive and micromechanical model for prediction of rate-dependent behavior of connective tissues (CTs) is presented. Connective tissues are considered as nonlinear viscoelastic material. The rate-dependent behavior of CTs is incorporated into model using the well-known quasi-linear viscoelasticity (QLV) theory. A planar wavy representative volume element (RVE) is considered based on the tissue microstructure histological evidences. The presented model parameters are identified based on the available experiments in the literature. The presented constitutive model introduced to ABAQUS by means of UMAT subroutine. Results show that, monotonic uniaxial test predictions of... 

    A validation study of a virtual-based haptic system for endoscopic sinus surgery training

    , Article International Journal of Medical Robotics and Computer Assisted Surgery ; Volume 15, Issue 6 , 2019 ; 14785951 (ISSN) Sadeghnejad, S ; Khadivar, F ; Abdollahi, E ; Moradi, H ; Farahmand, F ; Sadr Hosseini, S. M ; Vossoughi, G ; Sharif University of Technology
    John Wiley and Sons Ltd  2019
    Abstract
    Background: The development of endoscopic sinus surgery (ESS) training simulators for clinical environment applications has reduced the existing shortcomings in conventional teaching methods, creating a standard environment for trainers and trainees in a more accurate and repeatable fashion. Materials and methods: In this research, the validation study of an ESS training simulator has been addressed. It is important to consider components that guide trainees to improve their hand movements control in the orbital floor removal in an ESS operation. Therefore, we defined three tasks to perform: pre-experiment learning, training, and evaluation. In these tasks, the critical regions introduced in... 

    Relative performances of artificial neural network and regression mapping tools in evaluation of spinal loads and muscle forces during static lifting

    , Article Journal of Biomechanics ; Volume 46, Issue 8 , 2013 , Pages 1454-1462 ; 00219290 (ISSN) Arjmand, N ; Ekrami, O ; Shirazi Adl, A ; Plamondon, A ; Parnianpour, M ; Sharif University of Technology
    2013
    Abstract
    Two artificial neural networks (ANNs) are constructed, trained, and tested to map inputs of a complex trunk finite element (FE) model to its outputs for spinal loads and muscle forces. Five input variables (thorax flexion angle, load magnitude, its anterior and lateral positions, load handling technique, i.e., one- or two-handed static lifting) and four model outputs (L4-L5 and L5-S1 disc compression and anterior-posterior shear forces) for spinal loads and 76 model outputs (forces in individual trunk muscles) are considered. Moreover, full quadratic regression equations mapping input-outputs of the model developed here for muscle forces and previously for spine loads are used to compare the...