Search for: tandem-mass-spectrometry
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    Evaluation of bio-compatible poly(ethylene glycol)-based solid-phase microextraction fiber for in vivo pharmacokinetic studies of diazepam in dogs

    , Article Analyst ; Volume 132, Issue 7 , 2007 , Pages 672-678 ; 00032654 (ISSN) Es-Haghi, A ; Zhang, X ; Musteata, F. M ; Bagheri, H ; Pawliszyn, J ; Sharif University of Technology
    Royal Society of Chemistry  2007
    Solid-phase microextraction probes based on poly(ethylene glycol)/C18-bonded silica were used for in vivo monitoring of drugs from circulating blood of beagles, over a period of 8 h. After sampling, the extracted drugs were subsequently quantified by liquid chromatography coupled with tandem mass spectrometry. External calibrations in whole blood and phosphate-buffered saline were used to correlate the amount of analytes extracted in regard to the total and free concentrations in blood respectively. The probe provided sufficient sensitivity for the drugs in the blood matrix, while the need for drawing blood was eliminated. The limit of detections of the method from whole blood were 1.7, 1.4... 

    Analysis of alternative new pesticide (fluopyram, flupyradifurone, and indaziflam) residues in pistachio, date, and soil by liquid chromatography triple quadrupole tandem mass spectrometry

    , Article Soil and Sediment Contamination ; Volume 30, Issue 4 , 2021 , Pages 373-383 ; 15320383 (ISSN) Mahdavi, V ; Keikavousi Behbahan, A ; Moradi, F ; Aboul Enein, H. Y ; Sharif University of Technology
    Bellwether Publishing, Ltd  2021
    Fluopyram, flupyradifurone, and indaziflam are novel systemic pesticides developed by Bayer. Based on available data, these pesticides appears to have a favorable safety profile in the case of pesticide residue problems. Herein, we report an effective analytical method for the determination of novel pesticides were developed using ultra-high performance liquid chromatography with tandem mass spectrometry coupled with a quick, easy, cheap, effective, rugged, and safe procedure. These target compounds were extracted with acetonitrile and cleaned up with PSA, and were separated successfully between 10.2 and 18.3 min using a C18 chromatographic column connected to an electrospray ionization... 

    Preparation and evaluation of various banana-based biochars together with ultra-high performance liquid chromatography-tandem mass spectrometry for determination of diverse pesticides in fruiting vegetables

    , Article Food Chemistry ; Volume 360 , 2021 ; 03088146 (ISSN) Keikavousi Behbahan, A ; Mahdavi, V ; Roustaei, Z ; Bagheri, H ; Sharif University of Technology
    Elsevier Ltd  2021
    Biomass, originates from plant- or animal-based materials with a huge potential to be reused. Here we report a simple, rapid and inexpensive method for preparation of modified biochars derived from the banana peel followed by their applications in pipette-tip micro solid-phase extraction (PT-µSPE). Due to the contribution of various effective parameters on modification of banana peel biochars (BPBs), Taguchi design was used to optimize activation temperature, activation repetition, treatment material and impregnation ratio. Efficiency of the prepared BPBs were studied by extraction of twelve various pesticides, as model analytes with an extended range of log P values (1.4–5.7), followed by...