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tannic-acid
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Mint Flavor Immobilization and Properties Determination
, M.Sc. Thesis Sharif University of Technology ; Alemzadeh, Iran (Supervisor) ; Kazemi, Akhtarelmolook (Supervisor)
Abstract
Peppermint oil is one of the most often used food ingredients and it is volatile. Many common procedures such as microencapsulation have been used for protecting volatile food ingredients. For this research, L-menthol was chosen as the core material to be encapsulated. L-menthol is responsible for the minty flavor and cooling sensation of food and pharmaceutical products. The encapsulation of L-menthol was prepared by complex coacervation, using gum Arabic and gelatin as wall material and tannic acid as cross-linking agent. The effect of various processing parameters, including wall material, core material, tannic acid and tween¬80 concentrations, on particle size and efficiency was...
Encapsulation of peppermint oil with arabic gum-gelatin by complex coacervation method
, Article International Journal of Engineering, Transactions B: Applications ; Volume 26, Issue 8 , 2013 , Pages 807-814 ; 10252495 (ISSN) ; Alemzadeh, I ; Kazemi, A ; Sharif University of Technology
2013
Abstract
The gelatin/gum arabic microcapsules encapsulating peppermint oil were prepared by complex coacervationusing tannic acid as hardening agent. The effects of various parameters, including concentration of wall material, core material, tannic acid and Tween 80 were investigated on particle size and encapsulation efficiency. For statistical evaluation of the parameters, Taguchi method was concerned. The size of prepared spherical microcapsules was 19-66 micrometers. The results showed that, particle size increased with increasing the core and the wall concentration and decreased with increasing tannic acid and Tween 80 concentraIfd efficiency increased by increasing the core and wall...
Investigation on Effect of Additives on the Synthesis of Mesoporous Silica Nano Particles for Drug Delivery Applications
, M.Sc. Thesis Sharif University of Technology ; Nemati, Ali (Supervisor) ; Akbari, Hmid (Supervisor) ; Khoobi Shourkaei, Mahdi (Co-Supervisor)
Abstract
In recent years, the use of mesoporous silica nanoparticles as carriers of biological agents has increased. The use of nanometer dimensions in intra-body applications not only hides the particles from the view of macrophages and the body's immune system, but also causes the particles to enter the cells more easily through endocytosis. Template removal method is the most common method in the synthesis of mesoporous silica. In this method, the orderly arrangement of pattern-forming molecules is used to form pores. Until now, various types of organic materials have been used as pattern materials. The main goal is the synthesis of nanoparticles with the largest size of holes and the largest...
, M.Sc. Thesis Sharif University of Technology ; Yoozbashizadeh, Hossein (Supervisor) ; Moradkhani, Davoud (Supervisor)
Abstract
The environmental pollutions besides wasting the valuable materials as two main challenges in pyrometallurgical processes have brought up the tendency towards the hydrometallurgical processes. In the present study, the recovery of germanium from leaching residues of zinc plant has been investigated. Firstly, the required tests for concentrating the residues through washing of the zinc were designed by taguchi method, and optimum condition for maximum leaching of zinc accompanied by minimum desolution of germanium were obtained. The sulfuric acid concentration, time, termperature of reaction, solid to liquid ratio and rate of stirring are the parameters studied in this research. The obtained...
A hydrogen-bonded extracellular matrix-mimicking bactericidal hydrogel with radical scavenging and hemostatic function for ph-responsive wound healing acceleration
, Article Advanced Healthcare Materials ; 2020 ; Correia, A ; Hasany, M ; Figueiredo, P ; Dobakhti, F ; Eskandari, M. R ; Hosseini, H ; Abiri, R ; Khorshid, S ; Hirvonen, J ; Santos, H. A ; Shahbazi, M. A ; Sharif University of Technology
Wiley-VCH Verlag
2020
Abstract
Generation of reactive oxygen species, delayed blood clotting, prolonged inflammation, bacterial infection, and slow cell proliferation are the main challenges of effective wound repair. Herein, a multifunctional extracellular matrix-mimicking hydrogel is fabricated through abundant hydrogen bonding among the functional groups of gelatin and tannic acid (TA) as a green chemistry approach. The hydrogel shows adjustable physicochemical properties by altering the concentration of TA and it represents high safety features both in vitro and in vivo on fibroblasts, red blood cells, and mice organs. In addition to the merit of facile encapsulation of cell proliferation-inducing hydrophilic drugs,...
Optimization and characterization of tannic acid loaded niosomes for enhanced antibacterial and anti-biofilm activities
, Article Advanced Powder Technology ; 2020 ; Akbarzadeh, I ; Nourouzian, D ; Mirzaie, A ; Bakhshandeh, H ; Sharif University of Technology
Elsevier B.V
2020
Abstract
The purpose of this study was to prepare and characterize an optimized system of tannic acid-loaded niosomes as a potential carrier for antibacterial and anti-biofilm delivery. The niosomal formulation was optimized using response surface methodology (RSM). The effects of the molar ratio of surfactant to cholesterol, drug concentration, and molar ratio of Span 60 to Tween 60 on particle size and drug entrapment efficiency of the niosomal nanocarrier were studied. The optimized nanoparticles were characterized in terms of the morphology, in vitro release profile, and antibacterial properties. Moreover, Fourier-transform infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC)...
Advances in tannic acid-incorporated biomaterials: Infection treatment, regenerative medicine, cancer therapy, and biosensing
, Article Chemical Engineering Journal ; Volume 432 , 2022 ; 13858947 (ISSN) ; Rahimkhoei, V ; Abasian, P ; Delfi, M ; Naderi, J ; Ghomi, M ; Dabbagh Moghaddam, F ; Waqar, T ; Nuri Ertas, Y ; Sharifi, S ; Rabiee, N ; Ersoy, S ; Maleki, A ; Nazarzadeh Zare, E ; Sharifi, E ; Jabbari, E ; Makvandi, P ; Akbari, A ; Sharif University of Technology
Elsevier B.V
2022
Abstract
Polyphenol-based materials have attracted wide-spread interest from academic and industrial communities because of their unique structure and physicochemical properties. Tannic acid (TA), as a polyphenolic phytochemical with high level of galloyl groups, interacts with various substances (proteins, polysaccharides, and metals) through several modes including hydrogen bonding, hydrophobic and electrostatic interactions. Such hybrid or hybrid-like systems allow the preparation of various advanced materials with promising applications in medicine. In this review, we highlight the recent advances of TA-incorporated materials in medical applications including drug delivery, tissue engineering,...