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tertiary-α-amino-phosphonate
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Synthesis of tertiary α-amino phosphonate by one-pot three-component coupling mediated by LPDE
, Article Tetrahedron ; Volume 59, Issue 28 , 2003 , Pages 5329-5332 ; 00404020 (ISSN) ; Saidi, M. R ; Sharif University of Technology
Elsevier Ltd
2003
Abstract
A very mild, efficient and simple method for the synthesis of tertiary α-amino phosphonates is reported by reaction of an aldehyde, a secondary amine and trialkylphosphite in ethereal solution of lithium perchlorate, LPDE, at ambient temperature with high yields. © 2003 Elsevier Science Ltd. All rights reserved