Loading...
Search for:
tetracycline
0.007 seconds
Coordination chemistry of metal–organic frameworks: Detection, adsorption, and photodegradation of tetracycline antibiotics and beyond
, Article Coordination Chemistry Reviews ; Volume 464 , 2022 ; 00108545 (ISSN) ; Molavi, H ; Tajahmadi, S ; Rezakazemi, M ; Amini, M ; Kamkar, M ; Rojas, O. J ; Arjmand, M ; Sharif University of Technology
Elsevier B.V
2022
Abstract
Tetracyclines (TCs) are a large family of broad-spectrum antibiotics with one of the highest aquatic persistence after release from humans and animals. Hence, TCs are known to generate antibiotic resistance along with estrogenic and other toxic effects in non-target organisms. Unfortunately, the detection and removal of TCs from aqueous matrices remain challenging. For this purpose, we review metal–organic frameworks (MOFs), which have emerged as effective alternatives, given their photocatalytic and adsorptive capabilities. MOFs exhibit large interactive surface area and tunable structure and pore size for fast mass transfer and strong host–guest interactions. Herein, these and other topics...
Synthesis, Characterization, and Enhanced Optical/Electronic Properties of g-C3N4 Nanosheets for Water Remediation
, Ph.D. Dissertation Sharif University of Technology ; Moshfegh, Alireza (Supervisor) ; Asgari, Reza (Supervisor) ; Naseri, Naimeh (Co-Supervisor)
Abstract
A global concern has arisen owing to rapid industrial development and population growth, resulting in energy scarcity and earth pollution. In this regard, developing green and sustainable methods for producing clean energy and solving environmental pollution problems have absorbed enormous attention. Among various auspicious strategies, semiconductor photocatalysis has been widely studied in recent years owing to its capabilities to obtain hydrogen as an energy carrier, to remove organic pollutants, and to reduce CO2 emission by converting solar energy into chemical energy. Recently, a metal-free semiconductor photocatalyst based on graphitic carbon nitride, g-C3N4, has received much...
Novel nano-porous hydrogel as a carrier matrix for oral delivery of tetracycline hydrochloride
, Article Colloids and Surfaces A: Physicochemical and Engineering Aspects ; Volume 392, Issue 1 , December , 2011 , Pages 16-24 ; 09277757 (ISSN) ; Pourjavadi, A ; Soleyman, R ; Sharif University of Technology
Abstract
A novel nano-porous hydrogel (NPH) was synthesized via graft copolymerization of sodium acrylate (Na-AA) and acrylamide (AAm) onto salep backbones and its application as a carrier matrix for oral delivery of tetracycline hydrochloride (TH) was investigated. The Taguchi method as a strong experimental design tool was used for synthesis optimization. The swelling behavior of optimum hydrogel was measured in various media. The hydrogel formation was confirmed by Fourier transform infrared spectroscopy (FT-IR) and thermogravimetrical analysis (TGA). The study of the surface morphology of the hydrogels using SEM and AFM showed a nanoporous (average pore size: 180. nm) structure for the sample...
Multifunctional tetracycline-loaded silica-coated core-shell magnetic nanoparticles: antibacterial, antibiofilm, and cytotoxic activities
, Article ACS Applied Bio Materials ; Volume 5, Issue 4 , 2022 , Pages 1731-1743 ; 25766422 (ISSN) ; Eshrati Yeganeh, F ; Yousefi, M ; Baniyaghoob, S ; Farasati Far, B ; Akbarzadeh, I ; Bigham, A ; Ashrafizadeh, M ; Rabiee, N ; Makvandi, P ; Saeb, M. R ; Sharif University of Technology
American Chemical Society
2022
Abstract
In the current study, the physicochemical and biological properties of tetracycline-loaded core-shell nanoparticles (Tet/Ni0.5Co0.5Fe2O4/SiO2 and Tet/CoFe2O4/SiO2) were investigated. The antibacterial activity of nanoparticles alone and in combination with tetracycline was investigated against a number of Gram-positive and Gram-negative bacteria for determining minimum inhibitory concentration (MIC) values. The MIC of Tet/Ni0.5Co0.5Fe2O4/SiO2 nanoparticles turned out to be significantly higher than that of Tet/CoFe2O4/SiO2 nanoparticles. Furthermore, Tet/Ni0.5Co0.5Fe2O4/SiO2 nanoparticles exhibited potent antibiofilm activity against pathogenic bacteria compared to Tet/CoFe2O4/SiO2...
Improving bactericidal performance of implant composite coatings by synergism between Melittin and tetracycline
, Article Journal of Materials Science: Materials in Medicine ; Volume 33, Issue 6 , 2022 ; 09574530 (ISSN) ; Ghorbani, M ; Pooshang Bagheri, K ; Shokrgozar, M. A ; Sharif University of Technology
Springer
2022
Abstract
Methicillin resistance Staphylococcus aureus bacteria (MRSA) are serious hazards of bone implants. The present study was aimed to use the potential synergistic effects of Melittin and tetracycline to prevent MRSA associated bone implant infection. Chitosan/bioactive glass nanoparticles/tetracycline composite coatings were deposited on hydrothermally etched titanium substrate. Melittin was then coated on composite coatings by drop casting method. The surfaces were analyzed by FTIR, XRD, and SEM instruments. Tetracycline in coatings revealed multifunctional behaviors include bone regeneration and antibacterial activity. Releasing ALP enzyme from MC3T3 cells increased by tetracycline, so it is...
Bioactive Nanocomposite Coatings Containing Anti-Bacterial Factors with Controlled Release on the Bone Implant
, Ph.D. Dissertation Sharif University of Technology ; Ghorbani, Mohammad (Supervisor) ; Shokrgozar, Mohammad Ali (Supervisor) ; Pooshang Bagheri, Kamran (Co-Supervisor)
Abstract
Aseptic loosening and infection are two major problems of bone implants. Aseptic loosening occurs due to poor cell growth and poor adhesion to the implant surface over time. Bone infection at the implant site occurs mainly by the staphylococcus aureus bacteria. In some cases, infection occurs in the short term and in the early times after implantation, and in some cases, infection occurs in later times. The aim of this study is to synthesize and evaluate antibacterial coatings, while having cell growth-promoting components and cell differentiation to solve bone implant problems simultaneously. Also, the issue of bacterial resistance to antibiotics and their risks in bone implants is another...
UV-prepared salep-based nanoporous hydrogel for controlled release of tetracycline hydrochloride in colon
, Article Journal of Photochemistry and Photobiology B: Biology ; Volume 102, Issue 3 , March , 2011 , Pages 232-240 ; 10111344 (ISSN) ; Pourjavadi, A ; Ghavami, S ; Soleyman, R ; Jafarpour, F ; Sharif University of Technology
2011
Abstract
A highly swelling nanoporous hydrogel (NPH) was synthesized via UV-irradiation graft copolymerization of acrylic acid (AA) onto salep backbone and its application as a carrier matrix for colonic delivery of tetracycline hydrochloride (TH) was investigated. Optimized synthesis of the hydrogel was performed by the classic method. The swelling behavior of optimum hydrogel was measured in different media. The hydrogel formation was confirmed by Fourier transform infrared spectroscopy (FTIR) and thermo-gravimetric analysis (TGA/DTG/DTA). The study of the surface morphology of hydrogels using SEM showed a nanoporous (average pore size: about 350 nm) structure for the sample obtained under...
Targeted nanomedicines for the treatment of bone disease and regeneration
, Article Medicinal Research Reviews ; Volume 41, Issue 3 , 2021 , Pages 1221-1254 ; 01986325 (ISSN) ; Zandi, N ; Mazaheri, M ; Luther, G. A ; Ghovvati, M ; Akbarzadeh, A ; Annabi, N ; Sharif University of Technology
John Wiley and Sons Inc
2021
Abstract
Targeted delivery by either passive or active targeting of therapeutics to the bone is an attractive treatment for various bone related diseases such as osteoporosis, osteosarcoma, multiple myeloma, and metastatic bone tumors. Engineering novel drug delivery carriers can increase therapeutic efficacy and minimize the risk of side effects. Developmnet of nanocarrier delivery systems is an interesting field of ongoing studies with opportunities to provide more effective therapies. In addition, preclinical nanomedicine research can open new opportunities for preclinical bone-targeted drug delivery; nevertheless, further research is needed to progress these therapies towards clinical...
Preparation of novel and highly active magnetic ternary structures (metal-organic framework/cobalt ferrite/graphene oxide) for effective visible-light-driven photocatalytic and photo-fenton-like degradation of organic contaminants
, Article Journal of Colloid and Interface Science ; Volume 602 , 2021 , Pages 73-94 ; 00219797 (ISSN) ; Kazemeini, M ; Mahmoodi, N. M ; Sharif University of Technology
Academic Press Inc
2021
Abstract
Herein, MIL-101(Fe), CoFe2O4, novel binary (MIL-101(Fe)/CoFe2O4, MIL-101(Fe)/GO and CoFe2O4/GO), and ternary (MIL-101(Fe)/CoFe2O4/(3%)GO and MIL-101(Fe)/CoFe2O4/(7%)GO) magnetic composites based upon the MIL-101(Fe) were synthesized. The XRD, FESEM, TEM, EDX, BET-BJH, FTIR, VSM, DRS, PL, EIS and other electrochemical analyses were applied to characterize samples. The MIL/CoFe2O4/(3%)GO demonstrated the best performance compared to other samples for visible light photocatalytic and photo-Fenton-like degradation of Direct Red 23 (DtR-23), Reactive Red 198 (ReR-198) dyes as well as Tetracycline Hydrochloride (TC-H) antibiotic. Degradation of dyes using the ternary composite after 70 min of...