Search for: therapeutic-application
A multichannel single-well sensor array for rapid and visual discrimination of catecholamine neurotransmitters, Article Sensors and Actuators, B: Chemical ; Volume 296 , 2019 ; 09254005 (ISSN) ; Hormozi Nezhad, M. R ; Maaza, M ; Sharif University of Technology
Elsevier B.V 2019
In this study, for rapid identification and discrimination of catecholamine neurotransmitters in the presence of ascorbic acid (AA), a tricolor fluorescence probe has been constructed by integrating three recognition elements including blue carbon dots (bCDs), green CdTe quantum dots (gQDs) and red CdTe quantum dots (rQDs) into a single well. The proposed array exhibited ternary fluorescence emissions at 450, 520 and 630 nm with an overall luminescent pink emission under a single wavelength excitation (365 nm). In order to produce distinct response patterns from a single fluorimetric test, the spectral changes and the corresponding color variations of the multichannel fluorescence probe were...
Emerging phospholipid nanobiomaterials for biomedical applications to lab-on-a-chip, drug delivery, and cellular engineering, Article ACS Applied Bio Materials ; 2021 ; 25766422 (ISSN) ; Rabiee, N ; Ahmadi, S ; Jahangiri, S ; Sajadi, S. M ; Akhavan, O ; Saeb, M. R ; Kwon, W ; Kim, M ; Hahn, S. K ; Sharif University of Technology
American Chemical Society 2021
The design of advanced nanobiomaterials to improve analytical accuracy and therapeutic efficacy has become an important prerequisite for the development of innovative nanomedicines. Recently, phospholipid nanobiomaterials including 2-methacryloyloxyethyl phosphorylcholine (MPC) have attracted great attention with remarkable characteristics such as resistance to nonspecific protein adsorption and cell adhesion for various biomedical applications. Despite many recent reports, there is a lack of comprehensive review on the phospholipid nanobiomaterials from synthesis to diagnostic and therapeutic applications. Here, we review the synthesis and characterization of phospholipid nanobiomaterials...
Multifunctional core-shell nanoplatforms (gold@graphene oxide) with mediated NIR thermal therapy to promote miRNA delivery, Article Nanomedicine: Nanotechnology, Biology, and Medicine ; Volume 14, Issue 6 , 2018 , Pages 1891-1903 ; 15499634 (ISSN) ; Akhavan, O ; Adeli, M ; Razzazan, S ; Dinarvand, R ; Zanganeh, S ; Soleimani, M ; Dinarvand, M ; Atyabi, F ; Sharif University of Technology
Elsevier Inc 2018
Recent insights into the nanomedicine have revealed that nanoplatforms enhance the efficacy of carrier in therapeutic applications. Here, multifunctional nanoplatforms were utilized in miRNA-101 delivery and NIR thermal therapy to induce apoptosis in breast cancer cells. Au nanorods (NRs) or nanospheres (NSs) covered with graphene oxide (GO) were prepared and functionalized with polyethylene glycol as a stabilizer and poly-L-arginine (P-L-Arg) as a targeting agent. In nanoplatforms, coupling Au@GO prepared stable structures with higher NIR reactivity. P-L-Arg substantially enhanced the cellular uptake and gene retardation of stuffs coated by them. However, rod-shape nanoplatforms indicated...