Sharif Digital Repository

Traumatic brain injury (TBI) has long been known as one of the most anonymous reasons for death around the world. This phenomenon has been under study for many years and yet it remains a question due to physiological, geometrical and computational complexity. Due to limitation in experimental study on human head, the finite element human head model with precise geometric characteristics and mechanical properties is essential. In this study, the visco-hyperelastic parameters of bovine brain extracted from experimental data and finite element simulations which validated by experimental results. Then a 3D human head including brain, skull, and the meninges is modeled using CT-scan and MRI data... 

This study aims to provide a multiscale model of traumatic brain injury including the three levels of macro, meso, and microscale information. In order to do this, a macroscale voxel-baed model of human head was constructed. The model was designed and generated to include mesoscale tissue information as well as a voxel-based approach to include voxel-based microscale data and to be coupled in a multiscale framework. Next, three different microscale models were constructed. The variations of fractional anisotropy within one standard deviation in the regions (including 60% to 70% of voxels) can change the stiffness of the tissue by up to the considerable amount of 40%. The microscale models... 

Traumatic brain injury (TBI) has long been known as one of the most anonymous reasons for death around the world. A presentation of a model of what happens in the process has been under study for many years; and yet it remains a question due to physiological, geometrical and computational complications. Although the modeling facilities for soft tissue modeling have improved, the precise CT-imaging of human head has revealed novel details of brain, skull and the interface (the meninges), a comprehensive FEM model of which is still being studied. This study aims to present an optimized model of human head after a comprehensive study of the previous models; which includes the brain, skull, and... 

Subdural hemorrhage (SDH) is one of the most common traumatic brain injuries. The mortality rate of SDH is over 30 percent. In addition, patients require to visit hospital for treatment and further healthcare. According to the costs of treatment and frequency of injuries, prevention of SDH is essential. 3D-Finite element modeling of human head is an appropriate tool for evaluation of injury risk and setting up a prevention tolerance criteria. The aim of this study is to create a 3D finite element model of human head with special consideration of vessels. Vessels are modeled by truss elements at current finite element models of human head; however, geometry of vessels is regarded as simple...