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tricyclic-antidepressants
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Microextraction of antidepressant drugs into syringes packed with a nanocomposite consisting of polydopamine, silver nanoparticles and polypyrrole
, Article Microchimica Acta ; Volume 183, Issue 1 , 2016 , Pages 195-202 ; 00263672 (ISSN) ; Bani Hashemi, S ; Zandian, F. K ; Sharif University of Technology
Springer-Verlag Wien
Abstract
We describe a nanocomposite prepared from polydopamine, silver nanoparticles, and polypyrrole (PDA-Ag-PPy) that can be used for the microextraction in packed syringe (MEPS) of tricyclic antidepressants from urine samples. The PDA-Ag-PPy composite was prepared in-situ by the reduction of silver ion - doped PPy during oxidative polymerization of dopamine. The PDA-Ag coatings on the nanoribbon – shaped PPy represent a highly porous, inorganic–organic hybrid nanomaterial that has a wide range of applications. The nanocomposite was characterized by FTIR and scanning electron microscopy. It is shown to be an efficient sorbent for the MEPS of the tricyclic antidepressants amitriptyline, imipramine...