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Whole genome sequencing of SARS-CoV2 strains circulating in Iran during five waves of pandemic
, Article PLoS ONE ; Volume 17, Issue 5 May , 2022 ; 19326203 (ISSN) ; Nejati, A ; Salimi, V ; Jandaghi, N.Z.S ; Sadeghi, K ; Abedi, A ; Zarchi, A. S ; Gouya, M. M ; Mokhtari Azad, T ; Sharif University of Technology
Public Library of Science
2022
Abstract
Purpose Whole genome sequencing of SARS-CoV2 is important to find useful information about the viral lineages, variants of interests and variants of concern. As there are not enough data about the circulating SARS-CoV2 variants in Iran, we sequenced 54 SARS-CoV2 genomes during the 5 waves of pandemic in Iran. Methods After viral RNA extraction from clinical samples collected during the COVID-19 pandemic, next generation sequencing was performed using the Nextseq platform. The sequencing data were analyzed and compared with reference sequences. Results During the 1st wave, V and L clades were detected. The second wave was recognized by G, GH and GR clades. Circulating clades during the 3rd...