Sharif Digital Repository

The water-gas shift reaction occurs competitively to the main reaction of the Ir-catalysed methanol carbonylation process. To study the effect of seven factors including temperature, pressure, iridium, ruthenium, methyl iodide, methyl acetate and water concentrations on the formation of hydrogen and carbon dioxide as a result of the water-gas shift reaction and other side reactions in the carbonylation of methanol to acetic acid, the experimental design method combined with response surface methodology (RSM) was utilised. Central composite design at five levels (with α=1.63) was used to design experiments. A quadratic model that included the main and interaction effects of variables for H 2...