Sharif Digital Repository

In this investigation, the idea of Visual Working Memory (VWM) mechanism modeling based on versatile fuzzy method; Active Learning method, is presented. Visual information process; retrieving and learning rely on the use of Ink Drop Spread (IDS) and Center of Gravity (COG) as spatial density convergence operators. IDS modeling is characterized by processing that uses intuitive pattern information instead of complex formulas, and it is capable of stable and fast convergence. Furthermore, because it approves that distortion in retrieving irrelative data is adaptive to avoid storing lots of repetitive external information in daily visualization. Subsequently, this distortion is analyzed via two... 

Cognitive functions such as working memory require integrated activity among different brain regions. Notably, entorhinal cortex (EC) activity is associated with the successful working memory task. Olfactory bulb (OB) oscillations are known as rhythms that modulate rhythmic activity in widespread brain regions during cognitive tasks. Since the OB is structurally connected to the EC, we hypothesized that OB could modulate EC activity during working memory performance. Herein, we explored OB–EC functional connectivity during spatial working memory performance by simultaneous recording local field potentials when rats performed a Y-maze task. Our results showed that the coherence of delta,... 

Storing information from incoming stimuli in working memory (WM) is essential for decision-making. The prefrontal cortex (PFC) plays a key role to support this process. Previous studies have characterized different neuronal populations in the PFC for working memory judgements based on whether an originally presented stimulus matches a subsequently presented one (matching-rule decision-making). However, much remains to be understood about this mechanism at the population level of PFC neurons. Here, we hypothesized differences in processing of feature vs. spatial WM within the PFC during a matching-rule decision-making task. To test this hypothesis, the modulation of neural activity within the... 

Background: It is important to improve verbal Working Memory (WM) in reading disability, as it is a key factor in learning. There are commercial verbal WM training programs, which have some short-term effects only on the verbal WM capacity, not reading. However, because of some weaknesses in current verbal WM training programs, researchers suggested designing and developing newly structured programs that particularly target educational functions such as reading skills. In the current double-blind randomized clinical trial study, we designed a new Verbal Working Memory-Balance (VWM-B) program which was carried out using a portable robotic device. The short-term effects of the VWM-B program,... 

Allergic rhinitis (AR) is a chronic inflammatory disease frequently associated with a deficit in learning and memory. Working memory is an important system for decision making and guidance, which depends on interactions between the ventral hippocampus (vHipp) and the prelimbic prefrontal cortex (plPFC). It is still unclear whether AR influences the activity and coupling of these brain areas, which consequently may impair working memory. The current study aimed to examine alterations of the vHipp-plPFC circuit in a rat model of AR. Our results show decreased working memory performance in AR animals, accompanied by a reduction of theta and gamma oscillations in plPFC. Also, AR reduces...