Study and Preparation of Coated Drug by PEG Biopolymer (PEGylation) for Release Controlling, M.Sc. Thesis Sharif University of Technology ; Vossoughi, Manoochehr (Supervisor) ; Sarbolouki, Mohammad Nabi (Supervisor)
Abstract
In the first part of this work, citric acid monomer was selected to produce dendrimer through the divergent method using logical conditions (for controlling its functional groups) on the base of poly (ethylene glycol) as the core. Triblock copolymers (ABA-type) of citric acid and poly (ethylene glycol) (PCA-PEG-PCA) as biocompatible compounds were synthesized in four different molecular weights and applied as nanocarriers. The structure definition of the molecules and nanoparticles were carried out using different spectroscopy methods. Diameter of the synthesized copolymers was investigated using dynamic light scattering (DLS) experiments and transmission electron microscopy (TEM) and it was...
Cataloging briefStudy and Preparation of Coated Drug by PEG Biopolymer (PEGylation) for Release Controlling, M.Sc. Thesis Sharif University of Technology ; Vossoughi, Manoochehr (Supervisor) ; Sarbolouki, Mohammad Nabi (Supervisor)
Abstract
In the first part of this work, citric acid monomer was selected to produce dendrimer through the divergent method using logical conditions (for controlling its functional groups) on the base of poly (ethylene glycol) as the core. Triblock copolymers (ABA-type) of citric acid and poly (ethylene glycol) (PCA-PEG-PCA) as biocompatible compounds were synthesized in four different molecular weights and applied as nanocarriers. The structure definition of the molecules and nanoparticles were carried out using different spectroscopy methods. Diameter of the synthesized copolymers was investigated using dynamic light scattering (DLS) experiments and transmission electron microscopy (TEM) and it was...
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