Bending Rigidity of Helical Microtubule structures

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Mortazavi, Hamed | 2010

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Type of Document: M.Sc. Thesis
Language: Farsi
Document No: 40900 (04)
University: Sharif University of Technology
Department: Physics
Advisor(s): Ejtehadi, Mohammad Reza
Abstract:
Microtubules are hollow cylindrical structures of 25 nanometer diameter inside cell membrane. Microtubule (MT) serves as a cell structure component and vesicular transport inside cell. It has been shown in recent researches that the persistence length in MTs is length dependent and increases about several times of counter length. Also helical structures of MTs have been found recently. In this research using Molecular Dynamic simulation of coarse-grained microtubular structures we compare persistence length of wild and helical microtubular structures. We show that the persistence length in helical structures is independent to the length.
Keywords:
Biophysics ; Molecular Dynamic Simulation ; Persistence Length ; Statistical Mechanics ; Micro Tubule

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