Effect of Bioglass Particle Size and Titania Morphology on the Bioactivity and Kinetics of Tissue Growth in Three-Dimensional Poly(ɛ-Caprolactone) Scaffolds with Controlled Pore Structure Produced by 3D-Printing Process, Ph.D. Dissertation Sharif University of Technology ; Bagheri, Reza (Supervisor) ; Vossoughi, Manouchehr (Supervisor) ; Simchi, Abdolreza (Co-Advisor)
Abstract
Polycaprolactone (PCL) scaffolds and its composites containing bioactive glass particles (45S5) and TiO2 nanostructures with pre-defined and controlled external and internal architecture were prepared via an indirect three-dimensional (3D) printing process. The scaffolds had an interconnected structure with macro- (400-500 μm) and micro- (~25 μm) pores. Bioactivity, mechanical behavior and kinetics of tissue growth in 3D scaffolds were studied. The size effect of biogactive glass particles (6 μm, 250 nm, <100 nm) and morphology of titania nanostructures (spherical, tube, leaf-like, and flower-like particles) were elaborated. The biogactive glass particles with different sizes were prepared...
Cataloging briefEffect of Bioglass Particle Size and Titania Morphology on the Bioactivity and Kinetics of Tissue Growth in Three-Dimensional Poly(ɛ-Caprolactone) Scaffolds with Controlled Pore Structure Produced by 3D-Printing Process, Ph.D. Dissertation Sharif University of Technology ; Bagheri, Reza (Supervisor) ; Vossoughi, Manouchehr (Supervisor) ; Simchi, Abdolreza (Co-Advisor)
Abstract
Polycaprolactone (PCL) scaffolds and its composites containing bioactive glass particles (45S5) and TiO2 nanostructures with pre-defined and controlled external and internal architecture were prepared via an indirect three-dimensional (3D) printing process. The scaffolds had an interconnected structure with macro- (400-500 μm) and micro- (~25 μm) pores. Bioactivity, mechanical behavior and kinetics of tissue growth in 3D scaffolds were studied. The size effect of biogactive glass particles (6 μm, 250 nm, <100 nm) and morphology of titania nanostructures (spherical, tube, leaf-like, and flower-like particles) were elaborated. The biogactive glass particles with different sizes were prepared...
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