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- Type of Document: M.Sc. Thesis
- Language: Farsi
- Document No: 42155 (06)
- University: Sharif University of Technology
- Department: Chemistry
- Advisor(s): Mtlobi Moghadam, Firouz
- Abstract:
- The one pot, three component 1,3-dipolar cycloaddition reaction of azomethine ylides with a series of new dipolarophiles (E)-3 -benzylidene- indolin-2 -ones in methanol under the reflux condition yields ,3′-dispiropyrrolidine oxindole library. The product is produced with high regioselectivity. Catalyst free, excellent yield , easy workup process, short reaction time, and convenient operation are the characteristics of this procedure. NMR and X-ray are used to determine the structure and stereochemistry of cycloadduct products.
- Keywords:
- 1,3-Dipolar-Cycloaddition Reaction ; Azomethine Ylide ; Dispirooxindol ; Tree-Component Reaction ; Spiropyrrolidine
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