Design and Construction of Alginate-Silica Nanocomposite and Its Application for Mammalian Cell Culture, M.Sc. Thesis Sharif University of Technology ; Vossughi, Manouchehr (Supervisor) ; Arpanaei, Ayyoob (Supervisor) ; Kabir Salmani, Maryam (Co-Advisor)
Abstract
Three sizes of silica nanoparticles (160±7, 450±10 and 600±25) were sythetized via template-removing method. The synthetized nanoparticles were functionalized with N-(2-aminoethyl)-3-aminopropyl trimethoxy-silane (EDS) to provide a positive charge on the surface of nanoparticles. BET analysis showed that the average pore diameter, surface area and pore volume of nanoparticles were 2.3 nm, 769 m2.g-1 and 0.44 cm3.g-1, respectively. showed that the Amine-functionalized silica nanoparticles were used to enhance the application of alginate polymer for 3D encapsulation of mammalian cells. Incorporating of silica nanoparticles can be suitable for the bead integrity and attachement of mammalian...
Cataloging briefDesign and Construction of Alginate-Silica Nanocomposite and Its Application for Mammalian Cell Culture, M.Sc. Thesis Sharif University of Technology ; Vossughi, Manouchehr (Supervisor) ; Arpanaei, Ayyoob (Supervisor) ; Kabir Salmani, Maryam (Co-Advisor)
Abstract
Three sizes of silica nanoparticles (160±7, 450±10 and 600±25) were sythetized via template-removing method. The synthetized nanoparticles were functionalized with N-(2-aminoethyl)-3-aminopropyl trimethoxy-silane (EDS) to provide a positive charge on the surface of nanoparticles. BET analysis showed that the average pore diameter, surface area and pore volume of nanoparticles were 2.3 nm, 769 m2.g-1 and 0.44 cm3.g-1, respectively. showed that the Amine-functionalized silica nanoparticles were used to enhance the application of alginate polymer for 3D encapsulation of mammalian cells. Incorporating of silica nanoparticles can be suitable for the bead integrity and attachement of mammalian...
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