Synthesis of Dextran-MA-Gly-Gly-NHNH2 Copolymer as a Possible Biodegradable and pH-responsive Carrier for Doxorubicin, M.Sc. Thesis Sharif University of Technology ; Pourjavadi, Ali (Supervisor)
Abstract
Some chemotherapy drugs have unpleasant side effects and use them due to the instability and low solubility in blood flow is associated with problems and limitations.To solve these problems, controlled drug delivery systems have been proposed. In this process, the polymer increased solubility, stability and low toxicity and the active drug realease in a particular tissue or controlled speed. Therefore be less adverse side effects. Dextran is the one of biocompatible and water-soluble polysaccharides that due to its unique characteristics, widely used as carriers in drug delivery. Dextran molecules can bind to drugs and increased solubility, stability, and reduce their side effects....
Cataloging briefSynthesis of Dextran-MA-Gly-Gly-NHNH2 Copolymer as a Possible Biodegradable and pH-responsive Carrier for Doxorubicin, M.Sc. Thesis Sharif University of Technology ; Pourjavadi, Ali (Supervisor)
Abstract
Some chemotherapy drugs have unpleasant side effects and use them due to the instability and low solubility in blood flow is associated with problems and limitations.To solve these problems, controlled drug delivery systems have been proposed. In this process, the polymer increased solubility, stability and low toxicity and the active drug realease in a particular tissue or controlled speed. Therefore be less adverse side effects. Dextran is the one of biocompatible and water-soluble polysaccharides that due to its unique characteristics, widely used as carriers in drug delivery. Dextran molecules can bind to drugs and increased solubility, stability, and reduce their side effects....
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