The Effect of Protein Corona on Doxorubicin Release from the Magnetic Mesoporous Silica Nanoparticles and the Effect of Polyethylene Glycol Coating on drug Delivery System, M.Sc. Thesis Sharif University of Technology ; Pourjavadi, Ali (Supervisor)
Abstract
The nanoparticles have been widely used in the field of physics, chemistry, electronics and mechanics because of their high surface area. One of their most important applications is in drug delivery systems as smart drug nanocarrier. Magnetic nanoparticles (including Fe2O3, Fe3O4) are the good candidates for this purpose. It is clear that, upon to entrance of nanoparticle into biological media (such as plasma), the surface of nanoparticles were covered by protein layers (protein corona). This layer is very stable and created new surface on the nanoparticles. The protein corona layer intracts with cellular receptors and determines the fate of nanoparticles. Protein corona covers the targeting...
Cataloging briefThe Effect of Protein Corona on Doxorubicin Release from the Magnetic Mesoporous Silica Nanoparticles and the Effect of Polyethylene Glycol Coating on drug Delivery System, M.Sc. Thesis Sharif University of Technology ; Pourjavadi, Ali (Supervisor)
Abstract
The nanoparticles have been widely used in the field of physics, chemistry, electronics and mechanics because of their high surface area. One of their most important applications is in drug delivery systems as smart drug nanocarrier. Magnetic nanoparticles (including Fe2O3, Fe3O4) are the good candidates for this purpose. It is clear that, upon to entrance of nanoparticle into biological media (such as plasma), the surface of nanoparticles were covered by protein layers (protein corona). This layer is very stable and created new surface on the nanoparticles. The protein corona layer intracts with cellular receptors and determines the fate of nanoparticles. Protein corona covers the targeting...
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