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Blood Pressure Measurement by using Pulse Transit Time

Mazaheri, Samaneh | 2015

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  1. Type of Document: M.Sc. Thesis
  2. Language: Farsi
  3. Document No: 46863 (05)
  4. University: Sharif University of Technology
  5. Department: Electrical Engineering
  6. Advisor(s): Zahedi, Edmond; Jahed, Mehran
  7. Abstract:
  8. Continuous and non-invasive blood pressure (BP) measurement systems generally utilize applanation tonometry and vascular unloading. Some of them satisfies the AAMI standards (|mean|<5, |SD|<8). Unfortunately they are hardly to be widely affordable due to the complicated mechanical structure and high production cost. Till now those devices are seldom being used in operation room and generally used in clinical researches. In 2000, a linear model using pulse transit time (PTT) to continuous and non-invasive blood pressure (BP) measurement was proposed. Due to the nonlinear performance parameters of the arteries, researchers have used nonlinear models to promote this method. Although the precision and accuracy of the presented models are reported to be acceptable in the literature, devices purely based on PTT have not yet been released commercially. One of the most important reasons is that these methods need calibration at regular intervals. This causes the system not to work alone.In this thesis we proposed a new model that can estimate systolic and diastolic BP based on PTT that derived from two PPG signals that recorded from two different part of the body (Carotid artery and toe). Due to the systolic and diastolic BP are independent of each other, to estimate each of them we defined a pulse transition time relating to systolic and diastolic BP. Based on morphological characteristics, two points were defined as characteristic points related to PTTs and PTTd, pulse transmission time for systolic and diastolic pressure respectively. This model was tested in 18 volunteers that they are healthy who have not been diagnosed to suffer from any chronic disease. In this experiment we recorded different dataset for each individual in a testing session and measured his BP one time before the test and we use this BP as reference and results for each data set is compared with this reference pressure. Measurement error of this model -0.33 ± 2.68 mmHg and 0.28 ± 2.93 mmHg for systolic blood pressure and diastolic blood pressure were obtained. Also we obtain linear regression slope of 0.9989 and 1.0945 for the model of systolic and diastolic blood pressure
  9. Keywords:
  10. Pulse Transit Time (PTT) ; Pulse Wave Velosity ; Blood Pressure Measurement

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