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The concentration of serum zinc in celiac patients compared to healthy subjects in tehran

Fathi, F ; Sharif University of Technology | 2013

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  1. Type of Document: Article
  2. Publisher: 2013
  3. Abstract:
  4. Aim: This study evaluated serum levels of zinc in patient with CD compare to healthy subjects. Background: Celiac disease (CD) is characterized by small intestinal malabsorption of nutrients as a consequence of ingestion of wheat gluten. Zinc is an essential trace element that it has vital biological functions. Patients and methods: Sera of 30 celiac cases and 30 healthy normal cohorts as control group were obtained. Atomic absorption spectrophotometer was employed for estimating serum zinc level. Results: Zinc concentrations in patients diagnosed with CD were significantly lower than healthy subjects (75.97±12 compared with 92.83±18, P-value < 0.0001). Conclusion: The result of this study shows that serum zinc concentration is decreased in celiac patients compare to healthy controls. Serum zinc may thus be a marker of CD in adults presenting with gastrointestinal symptoms
  5. Keywords:
  6. controlled study ; Disease marker ; Zinc ; Adult ; Atomic absorption spectrometry ; Celiac disease ; Clinical article ; Cohort analysis ; Atomic absorption spectrophotometer ; Female ; Gastrointestinal symptom ; Human ; Iran ; Male ; Prospective study ; Spectrophotometer ; Zinc blood level
  7. Source: Gastroenterology and Hepatology from Bed to Bench ; Volume 6, Issue 2 , 2013 , Pages 92-95 ; 20082258 (ISSN)
  8. URL: http://journals.sbmu.ac.ir/ghfbb/index.php/ghfbb/article/view/365