Colorimetric Determination of Tizanidine and Mercury (II) Based on Aggregation and Anti-aggregation of Gold Nanoparticles, M.Sc. Thesis Sharif University of Technology ; Hormozi Nezhad, Mohammad Reza (Supervisor)
Abstract
In the first section of this research, we have developed a simple and rapid colorimetric method for determination of tizanidine using citrate capped gold nanoparticles. Under optimal conditions, the AuNPs easily aggregate upon addition of tizanidine and the solution color changes from red to gray. This color change was followed using a UV-Vis spectrophotometer. The detection limit was calculated to be 0.48 µM. The method was successfully applied for determination of tizanidine in Spalex© tablets. In the last section, the anti-aggregation effect of Hg(II) on the tizanidine-AuNPs system was utilized with the aim of developing a colorimetric method for detection of Hg(II). Addition of...
Cataloging briefColorimetric Determination of Tizanidine and Mercury (II) Based on Aggregation and Anti-aggregation of Gold Nanoparticles, M.Sc. Thesis Sharif University of Technology ; Hormozi Nezhad, Mohammad Reza (Supervisor)
Abstract
In the first section of this research, we have developed a simple and rapid colorimetric method for determination of tizanidine using citrate capped gold nanoparticles. Under optimal conditions, the AuNPs easily aggregate upon addition of tizanidine and the solution color changes from red to gray. This color change was followed using a UV-Vis spectrophotometer. The detection limit was calculated to be 0.48 µM. The method was successfully applied for determination of tizanidine in Spalex© tablets. In the last section, the anti-aggregation effect of Hg(II) on the tizanidine-AuNPs system was utilized with the aim of developing a colorimetric method for detection of Hg(II). Addition of...
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