A Novel Approach in DNA Sequencing Based on Physical Differences of Nucleotides, M.Sc. Thesis Sharif University of Technology ; Nejat Pishkenari, Hossein (Supervisor) ; Meghdari, Ali (Supervisor) ; Vossoughi, Gholamreza (Supervisor)
Abstract
With the continued improvement of sequencing technologies, the prospect of genome-based medicine is now at the forefront of scientific research. To realize this potential, however, a revolutionary sequencing method is needed for the cost-effective and rapid interrogation of individual genomes. Generally there are key factors in the definition and evalution of sequencing methods: 1-read length, 2-throughput, 3-read accuracy, 4-read depth, and 5-cost per base. The purpose of developing new sequencing methods is making better at least one of these factors. In order to reach the goal of rapid and low-cost sequencing method, one cannot rely only on current techniques. Improvements of current...
Cataloging briefA Novel Approach in DNA Sequencing Based on Physical Differences of Nucleotides, M.Sc. Thesis Sharif University of Technology ; Nejat Pishkenari, Hossein (Supervisor) ; Meghdari, Ali (Supervisor) ; Vossoughi, Gholamreza (Supervisor)
Abstract
With the continued improvement of sequencing technologies, the prospect of genome-based medicine is now at the forefront of scientific research. To realize this potential, however, a revolutionary sequencing method is needed for the cost-effective and rapid interrogation of individual genomes. Generally there are key factors in the definition and evalution of sequencing methods: 1-read length, 2-throughput, 3-read accuracy, 4-read depth, and 5-cost per base. The purpose of developing new sequencing methods is making better at least one of these factors. In order to reach the goal of rapid and low-cost sequencing method, one cannot rely only on current techniques. Improvements of current...
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