Modification of Gd-DTPA Contrast Agent for Targeted Drug Delivery be Nano Delivery, M.Sc. Thesis Sharif University of Technology ; Hamid Reza, Maddah Hosseini (Supervisor) ; Amo Abedini, Ghasem (Supervisor)
Abstract
One of the most useful method in medical imaging is Magnetic Resonance Imaging. Gadolinium base contrast agents used to improve images contrast made by MRI. There are some problems with using these drugs, such as toxicity and lack of targeting. In this research, Silicon nanoparticles were produced by a new fashion of removing template method. Particle size was scanned by Dynamic light scattering (DLS), mesoporous structure was investigated by Brunauer-Emmett-Teller (BET), and amine functionalization was recognized by Fourier transform infrared (FTIR). Functionality was determined by evaluation of signal and relaxation of nanoparticles.T1 was defined by a 1.5 tesla power MRI device. The...
Cataloging briefModification of Gd-DTPA Contrast Agent for Targeted Drug Delivery be Nano Delivery, M.Sc. Thesis Sharif University of Technology ; Hamid Reza, Maddah Hosseini (Supervisor) ; Amo Abedini, Ghasem (Supervisor)
Abstract
One of the most useful method in medical imaging is Magnetic Resonance Imaging. Gadolinium base contrast agents used to improve images contrast made by MRI. There are some problems with using these drugs, such as toxicity and lack of targeting. In this research, Silicon nanoparticles were produced by a new fashion of removing template method. Particle size was scanned by Dynamic light scattering (DLS), mesoporous structure was investigated by Brunauer-Emmett-Teller (BET), and amine functionalization was recognized by Fourier transform infrared (FTIR). Functionality was determined by evaluation of signal and relaxation of nanoparticles.T1 was defined by a 1.5 tesla power MRI device. The...
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