Combination of PRP (platelet Rich plasma)with Polymeric Scaffold for Cartilage Regeneration, M.Sc. Thesis Sharif University of Technology ; Abdekhodaei, Mohammad Jafar (Supervisor)
Abstract
The aim of this study is the fabrication of 3D porous PCL scaffolds contain core-shell fibers for cartilage tissue engineering. The novel fabrication method is co-axial wet electrospinning simultaneously. These tablets like scaffolds have superior porosity and pore sizes for cell culturing and cell-cell interaction as they have good mechanical properties for cartilage tissue engineering in comparison to 2D electrospun scaffolds. The structure of these 3D scaffolds is mimicking the ECM of cartilage. This study presents the coaxial electrospinning of PCL nanofibers encapsulated with bovine serum albumin and platelet rich plasma for demonstration of controlled release and bioactivity retention,...
Cataloging briefCombination of PRP (platelet Rich plasma)with Polymeric Scaffold for Cartilage Regeneration, M.Sc. Thesis Sharif University of Technology ; Abdekhodaei, Mohammad Jafar (Supervisor)
Abstract
The aim of this study is the fabrication of 3D porous PCL scaffolds contain core-shell fibers for cartilage tissue engineering. The novel fabrication method is co-axial wet electrospinning simultaneously. These tablets like scaffolds have superior porosity and pore sizes for cell culturing and cell-cell interaction as they have good mechanical properties for cartilage tissue engineering in comparison to 2D electrospun scaffolds. The structure of these 3D scaffolds is mimicking the ECM of cartilage. This study presents the coaxial electrospinning of PCL nanofibers encapsulated with bovine serum albumin and platelet rich plasma for demonstration of controlled release and bioactivity retention,...
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