Preparation and Evaluation of Doxorubicin-loaded Fe3O4\Chitosan Magnetic Nanocomposite for Drug Delivery System in Cancer Therapy, M.Sc. Thesis Sharif University of Technology ; Maddah Hosseini, Hamid Reza (Supervisor)
Abstract
Recent drug delivery strategies have attempted to maximize the concentration of chemotherapeutic molecules into the tumors, while minimizing their systemic distribution. Doxorubicin has been widely used for a variety of cancers, successfully producing regression in acute leukaemia, lymphomas, soft-tissue and osteogenic sarcomas, paediatric malignancies and adult solid tumours, in particular breast and lung carcinomas. Common adverse effects of doxorubicin include hair loss, myelosuppression, nausea and vomiting, oral mucositis, oesophagitis, diarrhoea, skin reactions and serious reactions include hypersensitivity reactions, radiation recall, heart damage and liver dysfunction. Chitosan has...
Cataloging briefPreparation and Evaluation of Doxorubicin-loaded Fe3O4\Chitosan Magnetic Nanocomposite for Drug Delivery System in Cancer Therapy, M.Sc. Thesis Sharif University of Technology ; Maddah Hosseini, Hamid Reza (Supervisor)
Abstract
Recent drug delivery strategies have attempted to maximize the concentration of chemotherapeutic molecules into the tumors, while minimizing their systemic distribution. Doxorubicin has been widely used for a variety of cancers, successfully producing regression in acute leukaemia, lymphomas, soft-tissue and osteogenic sarcomas, paediatric malignancies and adult solid tumours, in particular breast and lung carcinomas. Common adverse effects of doxorubicin include hair loss, myelosuppression, nausea and vomiting, oral mucositis, oesophagitis, diarrhoea, skin reactions and serious reactions include hypersensitivity reactions, radiation recall, heart damage and liver dysfunction. Chitosan has...
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