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Rapid and efficient one-pot synthesis of 1,4-dihydropyridine and polyhydroquinoline derivatives through the hantzsch four component condensation by zinc oxide

Matloubi Moghaddam, F ; Sharif University of Technology | 2009

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  1. Type of Document: Article
  2. Publisher: 2009
  3. Abstract:
  4. A one-pot four-component reaction of aldehydes, ethyl acetoacetate/5,5-dimethyl-1,3-cyclohexanedione, ethyl acetoacetate and ammonium acetate in the presence of 10 mol% of ZnO as a heterogeneous catalyst for the synthesis of corresponding 1,4-dihydropyridine and polyhydroquinoline derivatives via the Hantzsch condensation is described. The present methodology offers several advantages such as simple procedure, excellent yields, and short reaction time
  5. Keywords:
  6. 1,4-dihydropyridine and polyhydroquinolin ; Hantzsch condensation ; One-pot synthesis ; Zinc oxide
  7. Source: Journal of the Iranian Chemical Society ; Volume 6, Issue 2 , 2009 , Pages 317-324 ; 1735207X (ISSN)
  8. URL: https://link.springer.com/article/10.1007/BF03245840