Synthesis of Hydroxyapatite Nanoparticles through Sol-Gel Method and Fabrication of Chitosan/Hydroxyapatite Scaffold for Bone Replacement Tissue, M.Sc. Thesis Sharif University of Technology ; Nemati, Ali (Supervisor) ; Faghihi Sani, Mohammad Ali (Co-Supervisor)
Abstract
Hydroxyapatite is the most substantial inorganic component of bone tissue which displays great biocompability and bioactivity. Nevertheless, its mechanical properties is not appropriate for a bone substitiues. Therefore, it is used to improve the mechanical properties of polymer matrix composite scaffolds. In the present work chitosan as a polymeric matrix was employed to fabricate hydroxyapatite- chitosan biocomposite scaffolds. Sol-Gel method was employed to synthesize hydroxyapatite nano particles. Porous scaffolds were fabricated via freeze-drying by introducing two different cross linkers, Glutaraldehyde and Sodium Tripolyphosphate. Mechanical (compressive strength), biocampability and...
Cataloging briefSynthesis of Hydroxyapatite Nanoparticles through Sol-Gel Method and Fabrication of Chitosan/Hydroxyapatite Scaffold for Bone Replacement Tissue, M.Sc. Thesis Sharif University of Technology ; Nemati, Ali (Supervisor) ; Faghihi Sani, Mohammad Ali (Co-Supervisor)
Abstract
Hydroxyapatite is the most substantial inorganic component of bone tissue which displays great biocompability and bioactivity. Nevertheless, its mechanical properties is not appropriate for a bone substitiues. Therefore, it is used to improve the mechanical properties of polymer matrix composite scaffolds. In the present work chitosan as a polymeric matrix was employed to fabricate hydroxyapatite- chitosan biocomposite scaffolds. Sol-Gel method was employed to synthesize hydroxyapatite nano particles. Porous scaffolds were fabricated via freeze-drying by introducing two different cross linkers, Glutaraldehyde and Sodium Tripolyphosphate. Mechanical (compressive strength), biocampability and...
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