Optimization of Combination Chemotherapy Problem with Uncertain Cell Cxycle, M.Sc. Thesis Sharif University of Technology ; Rafiee, Majid (Supervisor) ; Najafi, Mehdi (Supervisor)
Abstract
Nowadays, chemotherapy is one of the common ways to treat cancer. Although, chemotherapy is used to kill cancer cells , chemotherapy drugs also target healthy cells and tissues of the body. In practice, it is difficult to strike a balance between injectable doses of drugs and toxicity in the body, and physicians are always looking for an effective treatment plan. One of the most common drugs that physicians use in chemotherapy is cell-cycle-specific drugs. These types of chemotherapy drugs affect only a certain phase of cell cycle and to a certain extent. Since the lifetime of the cancer cells is uncertain, the effective use of these drugs depends on the correct injection time of the drugs...
Cataloging briefOptimization of Combination Chemotherapy Problem with Uncertain Cell Cxycle, M.Sc. Thesis Sharif University of Technology ; Rafiee, Majid (Supervisor) ; Najafi, Mehdi (Supervisor)
Abstract
Nowadays, chemotherapy is one of the common ways to treat cancer. Although, chemotherapy is used to kill cancer cells , chemotherapy drugs also target healthy cells and tissues of the body. In practice, it is difficult to strike a balance between injectable doses of drugs and toxicity in the body, and physicians are always looking for an effective treatment plan. One of the most common drugs that physicians use in chemotherapy is cell-cycle-specific drugs. These types of chemotherapy drugs affect only a certain phase of cell cycle and to a certain extent. Since the lifetime of the cancer cells is uncertain, the effective use of these drugs depends on the correct injection time of the drugs...
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