Developing Protein-Loaded Modified Hyaluronic Acid Hydrogel for Tissue Regeneration, M.Sc. Thesis Sharif University of Technology ; Abdekhodaie, Mohammad Jafar (Supervisor)
Abstract
Growth factors play an important role in tissue repair and regeneration including articular cartilage tissue. Direct injection of growth factor is a common practice in clinics. However, it has been shown that this method is not very effective and, in some cases, induces some side effects. Moreover, incorporation of this valuable signals in systems where they are quickly released and washed out is not effective as well. Thereby the aim of this study was to design and fabricate an efficient system to effectively deliver growth factors for cartilage tissue engineering. The designed system is an injectable, in situ forming hydrogel, based on hyaluronic acid (HA) as a biocompatible and attractive...
Cataloging briefDeveloping Protein-Loaded Modified Hyaluronic Acid Hydrogel for Tissue Regeneration, M.Sc. Thesis Sharif University of Technology ; Abdekhodaie, Mohammad Jafar (Supervisor)
Abstract
Growth factors play an important role in tissue repair and regeneration including articular cartilage tissue. Direct injection of growth factor is a common practice in clinics. However, it has been shown that this method is not very effective and, in some cases, induces some side effects. Moreover, incorporation of this valuable signals in systems where they are quickly released and washed out is not effective as well. Thereby the aim of this study was to design and fabricate an efficient system to effectively deliver growth factors for cartilage tissue engineering. The designed system is an injectable, in situ forming hydrogel, based on hyaluronic acid (HA) as a biocompatible and attractive...
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