Micro-Nanofluidic Isolation of Circulating Exosomes from Blood Plasma, M.Sc. Thesis Sharif University of Technology ; Taghipoor, Mojtaba (Supervisor) ; saeedi, Mohammad saeed (Supervisor)
Abstract
Exosomes are a type of extracellular vesicles which are secreted by cells and could be found in all of human biofluids including blood. The size of exosomes is in the range of 30 – 150 nm. And they have a spherical structure with a phospholipid membrane. Exosomes are very important in academic research for the purpose of diagnostic and therapeutic practices because of their protein and nucleic acid contents.In this study a technological system was developed for isolation of circulating exosomes of human whole blood. This system consisted of a collection of microfluidic chips and protocols in order to extract a purified sample of exosomes from whole blood. First, a chip based on centrifugal...
Cataloging briefMicro-Nanofluidic Isolation of Circulating Exosomes from Blood Plasma, M.Sc. Thesis Sharif University of Technology ; Taghipoor, Mojtaba (Supervisor) ; saeedi, Mohammad saeed (Supervisor)
Abstract
Exosomes are a type of extracellular vesicles which are secreted by cells and could be found in all of human biofluids including blood. The size of exosomes is in the range of 30 – 150 nm. And they have a spherical structure with a phospholipid membrane. Exosomes are very important in academic research for the purpose of diagnostic and therapeutic practices because of their protein and nucleic acid contents.In this study a technological system was developed for isolation of circulating exosomes of human whole blood. This system consisted of a collection of microfluidic chips and protocols in order to extract a purified sample of exosomes from whole blood. First, a chip based on centrifugal...
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