Study and Fabrication of a Multilayer Scaffold Containing Biological Agents for Skin Wounds Regeneration, Ph.D. Dissertation Sharif University of Technology ; Alemzadeh, Iran (Supervisor) ; Vossoughi, Manouchehr (Supervisor) ; Shamloo, Amir (Co-Supervisor)
Abstract
In recent years, it is expected that the fabrication of multilayer scaffolds and the use of different methodologies in one product can be a new progressing method in skin substitute production. Accordingly, this project aims to fabricate a bilayered composite scaffold with a combination of hydrogel and electrospinning method. We have tried to prepare a scaffold made of oxidized alginate (OAL), gelatin (G), and silk fibroin (SF) without using corrosive solvents and toxic crosslinking agents as a scaffold and drug delivery system. As different biological, chemical, physical, and mechanical factors play a vital role in the healing process, we have characterized the proposed scaffold via DSC,...
Cataloging briefStudy and Fabrication of a Multilayer Scaffold Containing Biological Agents for Skin Wounds Regeneration, Ph.D. Dissertation Sharif University of Technology ; Alemzadeh, Iran (Supervisor) ; Vossoughi, Manouchehr (Supervisor) ; Shamloo, Amir (Co-Supervisor)
Abstract
In recent years, it is expected that the fabrication of multilayer scaffolds and the use of different methodologies in one product can be a new progressing method in skin substitute production. Accordingly, this project aims to fabricate a bilayered composite scaffold with a combination of hydrogel and electrospinning method. We have tried to prepare a scaffold made of oxidized alginate (OAL), gelatin (G), and silk fibroin (SF) without using corrosive solvents and toxic crosslinking agents as a scaffold and drug delivery system. As different biological, chemical, physical, and mechanical factors play a vital role in the healing process, we have characterized the proposed scaffold via DSC,...
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