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A novel copper-catalyzed synthesis of n-monosubstituted 2-alkynimi-damides from 1-alkynes and trichloroacetamidines

Fasihi Dastjerdi, H ; Sharif University of Technology | 2020

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  1. Type of Document: Article
  2. DOI: 10.2174/1570178616666191023142821
  3. Publisher: Bentham Science Publishers , 2020
  4. Abstract:
  5. A one-pot Cu-catalyzed synthesis of functionalized alkynyl imidamide by terminal alkynes, trichloroacetonitrile and aniline or benzyl amine is reported. The compounds were produced via coupling reaction of terminal alkynes with trichloroacetamidine. This method was performed under mild, ligand-free conditions and easy work-up method. © 2020, Bentham Science Publishers. All rights reserved
  6. Keywords:
  7. Alkynylimidamide ; Aniline ; Copper iodide ; Cross-coupling ; One-pot reaction ; Terminal alkynes
  8. Source: Letters in Organic Chemistry ; Volume 17, Issue 9 , 2020 , Pages 704-708
  9. URL: https://www.eurekaselect.com/176088/article