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Immobilization of synthesized phenyl-enriched magnetic nanoparticles in a fabricated Y–Y shaped micro-channel containing microscaled hedges as a microextraction platform

Rezvani, O ; Sharif University of Technology | 2020

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  1. Type of Document: Article
  2. DOI: 10.1016/j.aca.2020.08.034
  3. Publisher: Elsevier B.V , 2020
  4. Abstract:
  5. In this survey, a reliable and applicable Y–Y shaped micro–channel in a microfluidic device was designed and manufactured. A number of micro–scaled hedges were precisely fabricated inside the micro–channel to facilitate the immobilization of synthesized core–shell Fe3O4@SiO2 magnetic nanoparticles (MNPs), functionalized by triethoxyphenylsilane (TEPS) by sol-gel technique. Both sample and reagents were introduced into the microfluidic device by a syringe pump to perform the extraction and desorption steps. The functionalized MNPs were characterized by transmission electron microscopy, X-ray diffraction spectroscopy and Fourier transform infrared spectroscopy. By adopting the strategy of extraction–on–chip using this microfluidic device, we were benefited from implementing the entire analyses with the minimum amount of desorbing solvent, MNPs, and aqueous/fruit juice samples. In contrast to dispersive solid phase extraction, dispersion of MNPs during experiment is prevented by fabrication of micro-scaled hedges in the micro-channel. Consequently the stabilized MNPs are reused for the entire runs. The microfluidic device was successfully exploited as an efficient extracting plateau to evaluate the extraction/desorption capability in analysis of some organophosphorus pesticides (OPPs) as model compounds. Our results indicate that the functionalization of Fe3O4@SiO2 with TEPS, improved their extraction capability due to the existence of phenyl and hydroxyl groups for more efficient π–π and hydrogen bonding interactions. Eventually, μL-scale of the organic solvent was injected into a gas chromatography–mass spectrometry system. The limits of detection (3Sb) and quantification (10Sb) for the OPPs were 0.03–0.1 and 0.1–0.35 ng mL−1, respectively. In addition, the interday and intraday precisions were lower than 5.3% (n = 3). The obtained recovery was 95–99% for water samples and 88–96% for fruit juice samples while satisfactory regression coefficients of 0.9949–0.9991, could be achieved. © 2020 Elsevier B.V
  6. Keywords:
  7. Fruit juice ; Gas chromatography–mass spectrometry ; Organophosphorus pesticides ; Phenyl–enriched Fe3O4@SiO2 ; Y–Y shaped microfluidic device ; Desorption ; Fabrication ; Fluidic devices ; Fourier transform infrared spectroscopy ; Fruit juices ; Gas chromatography ; High resolution transmission electron microscopy ; Hydrogen bonds ; Iron oxides ; Magnetic nanoparticles ; Magnetite ; Mass spectrometry ; Microfluidics ; Phase separation ; Silica ; Silicon ; SiO2 nanoparticles ; Sol-gels ; Synthesis (chemical) ; Wooden fences ; Dispersive solid phase extraction ; Extraction capability ; Hydrogen bonding interactions ; Magnetic nanoparti cles (MNPs) ; Micro-fluidic devices ; Organophos-phorus pesticides ; Regression coefficient ; X-ray diffraction spectroscopy ; Extraction ; Chlorpyrifos ; Dimpylate ; Ethion ; Fenthion ; Magnetic nanoparticle ; Profenofos ; Silica nanoparticle ; Accuracy ; Aqueous solution ; Hydrogen bond ; Immobilization ; Limit of detection ; Limit of quantitation ; Mass fragmentography ; Microfluidics ; Priority journal ; Solid phase microextraction ; Synthesis ; Transmission electron microscopy ; X ray diffraction
  8. Source: Analytica Chimica Acta ; Volume 1136 , 2020 , Pages 51-61
  9. URL: https://www.sciencedirect.com/science/article/abs/pii/S0003267020308679