Robust Optimal Control of Drug Delivery in Cancer Chemotherapy based on a New Realistic Dynamic Model of the Process, M.Sc. Thesis Sharif University of Technology ; Moradi, Hamed (Supervisor)
Abstract
Today, cancer mortality is one of the most important problems, even considering the scientific advances that offer more effective solutions to treat some diseases, providing a way to prevent and treat this disease is one of the most important issues that engineers have considered. This is achieved by designing a controller to minimize the size of the cancer tumor population, increase healthy cells, optimize treatment time, and drug dose.To achieve this goal, pharmacokinetic, pharmacodynamic, tumor growth, and healthy cell growth models, and mathematical models for subsystems that affect tumor growth, such as the angiogenic system, have been studied to develop a single mathematical model. In...
Cataloging briefRobust Optimal Control of Drug Delivery in Cancer Chemotherapy based on a New Realistic Dynamic Model of the Process, M.Sc. Thesis Sharif University of Technology ; Moradi, Hamed (Supervisor)
Abstract
Today, cancer mortality is one of the most important problems, even considering the scientific advances that offer more effective solutions to treat some diseases, providing a way to prevent and treat this disease is one of the most important issues that engineers have considered. This is achieved by designing a controller to minimize the size of the cancer tumor population, increase healthy cells, optimize treatment time, and drug dose.To achieve this goal, pharmacokinetic, pharmacodynamic, tumor growth, and healthy cell growth models, and mathematical models for subsystems that affect tumor growth, such as the angiogenic system, have been studied to develop a single mathematical model. In...
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