A Systematic Approach for Biomarker Identification in Autism Spectrum Disorder based on Machine learning, M.Sc. Thesis Sharif University of Technology ; Jafari Siavoshani, Mahdi (Supervisor) ; Kavousi, Kaveh (Co-Supervisor) ; Ohadi, Mina (Co-Supervisor)
Abstract
Autism spectrum disorder (ASD) is a strong genetic perturbation that encompasses a wide range of clinical symptoms, including functional at different regions of the brain, repetitive behaviors, and interests, weaknesses in social relationships, some sensitivities to environmental factors and etc. Genetic complexity and the impact of environmental factors put the disease in the category of Level 1 complex developmental disorders.We proposed a pilot, combined, and highly effective structure to identify biomarkers in the autism spectrum disorder that could be extended to other diseases that have a similar genetic architecture with autism. We also develop a Gene-tissue interaction network to...
Cataloging briefA Systematic Approach for Biomarker Identification in Autism Spectrum Disorder based on Machine learning, M.Sc. Thesis Sharif University of Technology ; Jafari Siavoshani, Mahdi (Supervisor) ; Kavousi, Kaveh (Co-Supervisor) ; Ohadi, Mina (Co-Supervisor)
Abstract
Autism spectrum disorder (ASD) is a strong genetic perturbation that encompasses a wide range of clinical symptoms, including functional at different regions of the brain, repetitive behaviors, and interests, weaknesses in social relationships, some sensitivities to environmental factors and etc. Genetic complexity and the impact of environmental factors put the disease in the category of Level 1 complex developmental disorders.We proposed a pilot, combined, and highly effective structure to identify biomarkers in the autism spectrum disorder that could be extended to other diseases that have a similar genetic architecture with autism. We also develop a Gene-tissue interaction network to...
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