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Improved green biosynthesis of chitosan decorated Ag- and Co3O4-nanoparticles: A relationship between surface morphology, photocatalytic and biomedical applications

Kiani, M ; Sharif University of Technology | 2021

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  1. Type of Document: Article
  2. DOI: 10.1016/j.nano.2020.102331
  3. Publisher: Elsevier Inc , 2021
  4. Abstract:
  5. AgNPs@Chitosan and Co3O4-NPs@Chitosan were fabricated with Salvia hispanica. Results showed MZI values of 5 and 30 mm for Co3O4-NPs- and AgNPs@Chitosan against S. aureus, and 15 and 21 mm for Co3O4-NPs- and AgNPs@Chitosan against E. coli (24 h, 20 μg/mL), respectively. MTT assays showed up to 80% and 90%, 71% and 75%, and 91% and 94% mammalian cell viability for the green synthesized, chemically synthesized AgNPs and green synthesized AgNPs@Chitosan for HEK-293 and PC12 cells, respectively, and 70% and 71%, 59% and 62%, and 88% and 73% for the related Co3O4-NPs (24 h, 20 μg/mL). The photocatalytic activities showed dye degradation after 135 and 105 min for AgNPs@Chitosan and Co3O4-NPs@Chitosan, respectively. FESEM results showed differences in particle sizes (32 ± 3.0 nm for the AgNPs and 41 ± 3.0 nm for the Co3O4NPs) but AFM results showed lower roughness of the AgNPs@Chitosan (7.639 ± 0.85 nm) compared to Co3O4NPs@Chitosan (9.218 ± 0.93 nm), which resulted in potential biomedical applications. © 2020 Elsevier Inc
  6. Keywords:
  7. Biochemistry ; Escherichia coli ; Mammals ; Medical applications ; Morphology ; Photocatalytic activity ; Silver compounds ; Surface morphology ; Biomedical applications ; Dye degradation ; HEK-293 ; Mammalian cells ; MTT assays ; PC-12 cells ; Photo-catalytic ; S. aureus ; Chitosan ; Antibiotic agent ; Cobalt oxide nanoparticle ; Plant extract ; Salvia hispanica extract ; Silver nanoparticle ; Unclassified drug ; Antibacterial activity ; Atomic force microscopy ; Biosynthesis ; Cell proliferation ; Cell viability ; Chia ; Controlled study ; Cytotoxicity ; Cytotoxicity assay ; Degradation ; Fourier transform infrared spectroscopy ; HEK293 cell line ; Human ; Human cell ; Nonhuman ; Particle size ; PC12 cell line (pheochromocytoma) ; PH ; Photocatalysis ; Plant leaf ; Room temperature ; Scanning electron microscopy ; Staphylococcus aureus ; Surface property ; Ultraviolet irradiation ; Ultraviolet visible spectrophotometry ; Zone of inhibition
  8. Source: Nanomedicine: Nanotechnology, Biology, and Medicine ; Volume 32 , 2021 ; 15499634 (ISSN)
  9. URL: https://www.sciencedirect.com/science/article/abs/pii/S1549963420301854