Fast Alignment-free Protein Comparison Approach based on FPGA Implementation, M.Sc. Thesis Sharif University of Technology ; Koohi, Somayyeh (Supervisor)
Abstract
Protein, as the functional unit of the cell, plays a vital role in its biological function. With the advent of advanced sequencing techniques in recent years and the consequent exponential growth of the number of protein sequences extracted from diverse biological samples, their analysis, comparison, and classification have faced a considerable challenge. Existing methods for comparing proteins divide into two categories: methods based on alignment and alignment-free. Although alignment-based methods are among the most accurate methods, they face inherent limitations such as poor analysis of protein groups with low sequence similarity, time complexity, computational complexity, and memory...
Cataloging briefFast Alignment-free Protein Comparison Approach based on FPGA Implementation, M.Sc. Thesis Sharif University of Technology ; Koohi, Somayyeh (Supervisor)
Abstract
Protein, as the functional unit of the cell, plays a vital role in its biological function. With the advent of advanced sequencing techniques in recent years and the consequent exponential growth of the number of protein sequences extracted from diverse biological samples, their analysis, comparison, and classification have faced a considerable challenge. Existing methods for comparing proteins divide into two categories: methods based on alignment and alignment-free. Although alignment-based methods are among the most accurate methods, they face inherent limitations such as poor analysis of protein groups with low sequence similarity, time complexity, computational complexity, and memory...
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