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Aminoalkylation with aldehydes mediated by solid lithium perchlorate

Saidi, M. R ; Sharif University of Technology | 2004

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  1. Type of Document: Article
  2. DOI: 10.1007/s00706-003-0093-2
  3. Publisher: 2004
  4. Abstract:
  5. The solid LiClO4-mediated one-pot reaction of aldehydes with secondary amines and C nucleophiles afforded the corresponding aminoalkylation products in high yields. Unlike the previous reported procedure, the aminoalkylation of aldehyde was achieved in the presence of only 0.5 equivalents of solid lithium perchlorate in dichloromethane as the solvent with good to high yields at room temperature. © Springer-Verlag 2003
  6. Keywords:
  7. Aldehyde ; Aminoalkylation ; Mannich reaction ; Solid Lithium Perchlorate
  8. Source: Monatshefte fur Chemie ; Volume 135, Issue 3 , 2004 , Pages 309-312 ; 00269247 (ISSN)
  9. URL: https://link.springer.com/article/10.1007/s00706-003-0093-2