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Solvent-free three-component condensation reaction of aromatic ketones with aliphatic amines and formaldehyde

Mojtahedi, M. M ; Sharif University of Technology | 2000

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  1. Type of Document: Article
  2. DOI: 10.3184/030823400103167741
  3. Publisher: Scientific Reviews Ltd , 2000
  4. Abstract:
  5. A solvent-free procedure for the synthesis of several 1-aryl-2-(dialkylaminomethyl)-prop-2-en-1-ones 3 (a-e) and 4 (a-e) is reported. Reaction of arylmethyl ketones with formaldehyde and dialkylamines, such as diethyl- or dibutylamines at room temperature in silica gel produce 3 and 4 with moderate yields
  6. Keywords:
  7. Acrylic acid derivative ; Solvent ; Ketone derivative ; Formaldehyde ; Aromatic compound ; Aliphatic amine
  8. Source: Journal of Chemical Research - Part S ; Issue 8 , 2000 , Pages 380-381 ; 03082342 (ISSN)
  9. URL: https://journals.sagepub.com/doi/abs/10.3184/030823400103167741