Developing Novel Multiobjective Approaches for Direct Angle and Aperture Optimization Problem in Intensity Modulated Radiation Therapy, M.Sc. Thesis Sharif University of Technology ; Akhavan Niaki, Taghi (Supervisor) ; Mahnam, Mehdi (Co-Supervisor)
Abstract
Intensity-modulated radiation therapy is a well-known technique to treat cancer patients worldwide. A treatment plan in this technique requires decision-making for three main problems: selection of beam angles, intensity map calculation, and leaf sequencing. Previous works have investigated these problems sequentially. In this research, we present a new integrated framework for simultaneous decision-making of directions, intensities, and apertures shape, called direct angle and aperture optimization, and develop a mixed-integer nonlinear mathematical model for the problem. At first, the problem's single-objective model is established using the quadratic dose penalty function. After that,...
Cataloging briefDeveloping Novel Multiobjective Approaches for Direct Angle and Aperture Optimization Problem in Intensity Modulated Radiation Therapy, M.Sc. Thesis Sharif University of Technology ; Akhavan Niaki, Taghi (Supervisor) ; Mahnam, Mehdi (Co-Supervisor)
Abstract
Intensity-modulated radiation therapy is a well-known technique to treat cancer patients worldwide. A treatment plan in this technique requires decision-making for three main problems: selection of beam angles, intensity map calculation, and leaf sequencing. Previous works have investigated these problems sequentially. In this research, we present a new integrated framework for simultaneous decision-making of directions, intensities, and apertures shape, called direct angle and aperture optimization, and develop a mixed-integer nonlinear mathematical model for the problem. At first, the problem's single-objective model is established using the quadratic dose penalty function. After that,...
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