Synthesis of Amine-Functionalized BN Quantum Dots for Active Targeting of SKOV3 Cells and Cell Imaging in a Microfluidics System, M.Sc. Thesis Sharif University of Technology ; Simchi, Abdolreza (Supervisor) ; Mohammadi, Mohammad Reza (Supervisor)
Abstract
The biocompatibility and chemical stability of boron nitride nanomaterials surpass those of carbon nanomaterials. In addition, boron nitride nanomaterials share the same structure as graphene materials, making them a suitable replacement for graphene in biological applications. In this study, SKOV3 cancer cells were actively targeted using amine-functionalized boron nitride quantum dots that were covalently modified by CD133 antibody. Under the condition that they are not conjugated with antibody, these nanoparticles were also incorporated into the microfluidic device designed to image MCF7 cancer cells. These nanoparticles were produced via solvothermal synthesis in an organic solvent...
Cataloging briefSynthesis of Amine-Functionalized BN Quantum Dots for Active Targeting of SKOV3 Cells and Cell Imaging in a Microfluidics System, M.Sc. Thesis Sharif University of Technology ; Simchi, Abdolreza (Supervisor) ; Mohammadi, Mohammad Reza (Supervisor)
Abstract
The biocompatibility and chemical stability of boron nitride nanomaterials surpass those of carbon nanomaterials. In addition, boron nitride nanomaterials share the same structure as graphene materials, making them a suitable replacement for graphene in biological applications. In this study, SKOV3 cancer cells were actively targeted using amine-functionalized boron nitride quantum dots that were covalently modified by CD133 antibody. Under the condition that they are not conjugated with antibody, these nanoparticles were also incorporated into the microfluidic device designed to image MCF7 cancer cells. These nanoparticles were produced via solvothermal synthesis in an organic solvent...
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