Design, Optimization and Fabrication of Multiplex Scaffold for Tissue Engineering Applications, M.Sc. Thesis Sharif University of Technology ; Shamloo, Amir (Supervisor) ; Hosseini, Vahid (Supervisor)
Abstract
Cartilage is a connective tissue, whose most important role in the body is to create a surface with a low friction coefficient in order to allow bones to slide on each other without direct contact to transfer loads. Articular cartilage is always under a harsh biomechanical environment and lacks blood, lymphatic and nerve vessels. As a result, it limits the capacity of this tissue to improve and restore itself. According to experimental efforts, cartilage cannot be regenerated spontaneously without the support of healthy subchondral bone. In recent years, the implantation of tissue engineering scaffolds has been considered as an effective strategy for the treatment of osteochondral damage....
Cataloging briefDesign, Optimization and Fabrication of Multiplex Scaffold for Tissue Engineering Applications, M.Sc. Thesis Sharif University of Technology ; Shamloo, Amir (Supervisor) ; Hosseini, Vahid (Supervisor)
Abstract
Cartilage is a connective tissue, whose most important role in the body is to create a surface with a low friction coefficient in order to allow bones to slide on each other without direct contact to transfer loads. Articular cartilage is always under a harsh biomechanical environment and lacks blood, lymphatic and nerve vessels. As a result, it limits the capacity of this tissue to improve and restore itself. According to experimental efforts, cartilage cannot be regenerated spontaneously without the support of healthy subchondral bone. In recent years, the implantation of tissue engineering scaffolds has been considered as an effective strategy for the treatment of osteochondral damage....
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