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Evaluation and Analysis of tDCS and tACS in Improvement of Tinnitus Condition

Tajari, Ahmad Reza | 2023

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  1. Type of Document: M.Sc. Thesis
  2. Language: Farsi
  3. Document No: 56700 (05)
  4. University: Sharif University of Technology
  5. Department: Electrical Engineering
  6. Advisor(s): Jahed, Mehran; Hani Tabatabaie, Mozhgan; Asadpour, Abdureza
  7. Abstract:
  8. Tinnitus is variety of sounds heard when no corresponding external sound is present. To remedy this condition, various methods have been proposed, however none have resulted in systematic and lasting results. This study aims to investigate the efficacy of non-invasive electrical stimulation techniques (tES) in the treatment of tinnitus. Stimulation parameters, including intensity, frequency, duration, and session frequency, are tailored to the individual's subjective tinnitus characteristics and treatment goals. Specifically, transcranial direct current stimulation (tDCS) is explored as a non-invasive method of electrical stimulation. In the tDCS method, electrodes are strategically positioned on specific regions of the brain to deliver non-invasive electrical stimulation. By applying a low-intensity current of approximately 1-2 milliamps, targeted areas of the brain can be modulated. This technique induces immediate and long-term changes in neural activity patterns, potentially modulating the neural circuits associated with tinnitus perception. While the primary objective of this thesis is to propose and implement protocols and stimulation systems for both transcranial direct and alternating current stimulation, the overarching aim is to address challenges related to optimizing the effectiveness of these stimulation techniques for tinnitus treatment. Behavioral and cognitive measures stand as primary indicators, validated through an innovative approach involving the simultaneous recording of EEG signals and functional magnetic resonance images (fMRI). The study involves three individuals with tinnitus as well as three healthy participants, with a pilot session conducted prior to the main study to ensure feasibility of protocols. The results demonstrate significant improvements in both the loudness of sounds and the distress experienced by the participants
  9. Keywords:
  10. Tinnitus ; Transcranial Direct Current Stimulation (tDCS) ; Functional Magnetic Resonance Imaging (FMRI) ; Electroencphalogram ; Transcranial Alternative Current Stimulation (tACS) ; Functional Electrical Stimulation

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