Distributed Cardiovascular System Modeling

Khani, Mehrdad | 2009

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  1. Type of Document: M.Sc. Thesis
  2. Language: Farsi
  3. Document No: 39822 (05)
  4. University: Sharif University of Technology
  5. Department: Electrical Engineering
  6. Advisor(s): Jahed, Mehran
  7. Abstract:
  8. Simulation of cardiovascular system functionality during various physiological conditions is essential at different diagnostic and clinical levels. A first step in studying the roots of cardiovascular diseases and abnormal activity is to study a practical yet complete model of the cardiovascular system. In this thesis we introduced a new approach for defining the distributed model of the cardiovascular system. Initially, we chose an appropriate subsystem, namely Arch of Aorta, and proposed a distributed model for it. The elements of the proposed model were nonlinear RLC elements that simulate resistance, blood viscosity and vessel elasticity respectively. To minimize the system complexity, we calculated the parameters indirectly. Hence we measured the pressure and flow of blood at the input and output of the target block. Then Kalman filter and EKF method were analytically evaluated and parameter values were determined. Results indicate that by appropriately adjusting the nonlinear elements of the analogue model, the system was able to follow the distinct pressure profile of Aorta at various system variations. Our findings indicate that the proposed distributed modeling of cardiovascular system may be successfully applied towards building a comprehensive diagnostic and clinical tool
  9. Keywords:
  10. Cardiovascular System ; Extended Kalman Filter ; Kalman Filters ; Lumped Model ; Distributed Electric Model

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